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gcvP1

Gene
gcvP1
Protein
Glycine dehydrogenase (decarboxylating) 1
Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
Length
965 amino acids
Function
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
Similarity
Belongs to the GcvP family.
Mass
104.676 kDa
Sequence
MTSKTIVNSLAELEQTQDFIRRHIGPSESETQAMLNDLGVESVDALIDEIVPSDIRLADLPNVEESKTEVQALADLKAVASLNKVNDTYIGLGYFGTLTPNVILRNVLENPGWYTAYTPYQPEIAQGRLESLLNYQQMCIDLTGLELASASLLDEGTAAAEAMALAKRVSKNKKSNLFFISDDVYPQTIDVVKQRAEMFGFDIVVAPAADAAEHDIFGALIQYPGASGQVTDVSELIAKIHDNKGIVAVAADIMSLVLLKSPGELGADAVIGSSQRFGVPMGYGGPHAAFFTTLDKYKRSLPGRIIGVSKDTRGKNALRMAMQTREQHIRREKANSNVCTAQVLLANMAAFYAVYHGPQGLKTIANRIHRLADILCLGTATKGLTAVHANYFDTLTFNVDNKDEIVARALAANANFRTDVDGQISIALDETTTRENVAQLFDILLGEGHGLNVSDLDDQIVASGHSSIPASLVRESAILTHPVFNSYHSETEMLRYIKRLENKDLALNHSMISLGSCTMKLNATAQMIPVSWPEFANMHPFAPVNQAQGYKAMIDELAKWLVELTGYDKMSMQPNSGAQGEYAGLIAISKYHESRGDSHRNICLIPASAHGTNPASAMMVDMKIVIVACDKEGNVDMADLKAKAEELADNLACIMITYPSTHGVYETTIAEICNIIHDNGGQVYLDGANMNAQVGLTSPGFIGADVSHLNLHKTFAIPHGGGGPGMGPIGVKSHLAPFLPDHALINVDEATKGNGAVSSAPFGSASILPITYLYIALLGKKGVTDATKYAITNANYVSKKLSEHYPILYSGKNGRVAHECIVDLRPLKASSGVTEVDMAKRLMDYGFHSPTMSFPVAGTFMIEPTESESKVELDRFIEAMVCIRDEVRKVESGEWASDNNPLHNAPHTLADITEPWDRPYSIQEAVFPVVAVTANKFWPTVNRIDDVFGDRNLICSCPPIESYID

Gene
gcvP1
Protein
Glycine dehydrogenase (decarboxylating) 1
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
959 amino acids
Function
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).
Similarity
Belongs to the GcvP family.
Mass
103.919 kDa
Sequence
MTDNLNLGAIDLGTDDEFIARHIGPRAADTQAMLQRLGYDSLDTLIGNVIPDSIKGSSVLDLPAGMGEAEALASLKAIAARNRALRSFIGQGYYNCHTPAPILRNLLENPAWYTAYTPYQPEISQGRLEALLNFQTLVSDLSGLPIANASMLDEATAAAEAMTFCKRLSKNRTSQAFFASRHCHPQTLDVLRTRAEPLGIEVVVGDESTIEDFSAYFGALLQYPTCDGEIVDYRELVSRFHAVDALVAVAADLLALTLLTPPGEFGADVAIGSAQRFGVPLGFGGPHAAYFATRDAFKRDMPGRLVGVSIDRHGKPAYRLAMQTREQHIRREKATSNICTAQVLLANIASMFAVYHGPQGLLRIARRTHRLTAILAAGLERLGVAVEQKHFFDTLSLATGARTAAIHAKARAAGINLREIDAGRLGLSLDETVRQTDVETLWGLLAEEGQALPDFAALAASSGDRLPVELLRQSAILSHPIFNRHHSETELMRYLRKLADKDLALDRTMIPLGSCTMKLNAASEMIPVTWAEFGNLHPFAPAEQSEGYRQLTDELEAMLCSATGYDAVSLQPNAGSQGEYAGLLAIRAYHQSRGDSQRDICLIPSSAHGTNPATASMVGMRVVVVACDARGNVDVEDLRNKASEHKERLAALMITYPSTHGVFEEAIREICAIVHDCGGQVYIDGANMNAMVGLCAPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVRAHLAPFLPGHARGERKEGAVSAAPYGSASILPITWMYIRMMGGEGLKRASEMAILNANYIAHRLEEHYPVLYAGGNGLVAHECILDLRPLKDSSGISVDDVAKRLMDFGFHAPTMSFPVAGTLMIEPTESESKAELDRFCDAMIRIREEIRAVERGELDKEDNPLKNAPHTAAELLGEWNHAYSREQAAYPLASLVEAKYWPPVGRVDNVYGDRNLTCSCPPIEAYSEE

Gene
gcvP1
Protein
Glycine dehydrogenase (decarboxylating) 1
Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Length
951 amino acids
Function
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
Similarity
Belongs to the GcvP family.
Mass
102.473 kDa
Sequence
MTVNLSTANEFIARHIGPRQGDEQAMLNSLGFDSLEALSASVIPESIKGTSVLELGHGLSEAQALASIKAIAARNQLFKTYIGQGYYNCHTPSPILRNLLENPAWYTAYTPYQPEISQGRLEALLNFQTLISDLSGLPIANASLLDEGTAAAEAMTFCKRLSKNKGSHAFFASQHCHPQTLDVLRTRAEPLGINVVVGDERKLTDVSPFFGALLQYPASNGDLFDYRELTERFHAANALVAVAADLLALTLLTPPGEFGADVAIGSAQRFGVPLGFGGPHAAYFATRDAFKRDMPGRLVGVSVDRFGKPALRLAMQTREQHIRREKATSNICTAQVLLANIASMYAVYHGPKGLTQIAQRIHQLTAILAKGLVQLGLTVEQESFFDTLSLHTAGRTAALHDKARAQGINLRVIDAERLGLSLDETTTQADVETLWSLLADGKPAPDFAALAAAVTSGIPAALARQSAILSHPVFNRYHSETELMRYLRKLADKDLALDRTMIPLGSCTMKLNAASEMIPITWAEFGALHPFAPAEQSAGYQQLTTELEAMLCAATGYDAVSLQPNAGSQGEYAGLLAIRAYHQSRGDERRDICLIPSSAHGTNPATANMAGMRVVVTACDARGNVDIEDLRAKAIEHREHLAALMITYPSTHGVFEEGIREICGIIHDNGGQVYIDGANMNAMVGLCAPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVKSHLAPFLPGHAALENKKGAVCAAPFGSASILPITWMYISMMGGAGLKRASQLAILNANYISRRLEEHYPVLYTGSNGLVAHECILDLRPLKDSSGISVDDVAKRLIDFGFHAPTMSFPVAGTLMIEPTESESKEELDRFCDAMIRIREEIRAVENGALDKDDNPLKNAPHTAAELVGEWSHPYSREQAVYPVASLVEGKYWPPVGRVDNVFGDRNLVCACPSIESYQDA

Gene
gcvP1
Protein
Glycine dehydrogenase (decarboxylating) 1
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Length
951 amino acids
Function
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).
Similarity
Belongs to the GcvP family.
Mass
101.992 kDa
Sequence
MTINLGTANEFIARHIGPRAADEQAMLTALGFDSLDAMTAAVIPDSIKGTSVLGSHDGQSEADALAALKAIAGKNQLFKSYIGQGYYNTHTPAPILRNLLENPAWYTAYTPYQPEISQGRLEALLNFQTLISDLTGLPIANASLLDEATAAAEAMTFCKRLSKNKSSHAFFASVHCHPQTLDVLRTRAEPLGIEVVVGDERELGDVSAFFGALLQYPASNGEVFDYREVVQRFHAANALVAVAADLLALTLLTPPGEFDADVAIGSAQRFGVPLGFGGPHAAYFATRDAFKRDMPGRLVGVSIDRFGKTALRLAMQTREQHIRREKATSNICTAQVLLANIASMFAVYHGPAGLKRIAERTHALTAILAAGLKALGVQVVGASAFDTLTLATGTATASLHDKARAQGINLRQIDAAHVGLSLDETSTQADVESLWQLLGGEQAQPDFTALAASTGSLLPAALLRQSAILEHPVFNRYHSETELMRYLRRLADKDLALDRSMIPLGSCTMKLNAASEMIPVTWAEFGNLHPFAPAEQSQGYLQMTTELEAMLCAATGYDAVSLQPNAGSQGEYAGLLAIRAYHRSRGEGHRDICLIPSSAHGTNPATAHMAGMRVVVTACDARGNVDVEDLRAKAIEHRERLAAIMITYPSTHGVFEEAIGEICAIIHDNGGQVYIDGANMNAMVGLCAPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVKSHLAPFLPGHAQLENTQGAVCAAPFGSASILPITWMYIRMMGGAGLKRASQMAILNANYIARRLEEHYPVLYTGGNGLVAHECILDLRPLKDTSGISVDDVAKRLIDFGFHAPTMSFPVAGTLMIEPTESESKEELDRFCNAMIQIREEIRAVEDGSLDKDDNPLKNAPHTAAELVGEWTHGYSREQAVYPLASLVEGKYWPPVGRVDNVFGDRNLVCACPSIESYQDA

Gene
gcvP1
Protein
Glycine dehydrogenase (decarboxylating) 1
Organism
Pseudomonas fluorescens (strain Pf0-1)
Length
950 amino acids
Function
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
Similarity
Belongs to the GcvP family.
Mass
102.581 kDa
Sequence
MTQVNLGTANEFIARHIGPRAGDEQAMLNSLGFDSLEALSASVIPESIKGTSVLGLDDGLSEADALAMIKGIAGKNQLFKTYIGQGYYNCHTPSPILRNLLENPAWYTAYTPYQPEISQGRLEALLNFQTLISDLTGLPIANASLLDEATAAAEAMTFCKRLSKNKGSHQFFASIHSHTQTLDVLRTRAEPLGIDVVVGDERELTDVTPFFGALLQYPASNGDVFDYRELTERFHAANALVAVAADLLALTLLTPPGEFGADVAIGSAQRFGVPLGFGGPHAAYFSTKDAFKRDMPGRLVGVSVDRFGKPALRLAMQTREQHIRREKATSNICTAQVLLANIASMYAVYHGPKGLTQIANRVHHLTAILAKGLSALGVTVEQTSFFDTLTLATGAQTAALHDKARAQQINLRVIDAQRLGLSVDETTTQADIETLWGLFADGKTLPDFAALAAAAQSTIPASLVRQSPILSHPVFNRYHSETELMRYLRKLADKDLALDRTMIPLGSCTMKLNAASEMIPVTWAEFGALHPFAPAEQSAGYQQLTDELEAMLCAATGYDSISLQPNAGSQGEYAGLLAIRAYHQSRGEDRRDICLIPSSAHGTNPATANMAGMRVVVTACDARGNVDIEDLRAKAIEHREHLAALMITYPSTHGVFEEGIREICGIIHDNGGQVYIDGANMNAMVGLCAPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVKSHLTPFLPGHGHMERKEGAVCAAPFGSASILPITWMYIRMMGGAGLKRASQLAILNANYISRRLEEHYPVLYTGSNGLVAHECILDLRPLKDSSGISVDDVAKRLIDFGFHAPTMSFPVAGTLMIEPTESESKEELDRFCDAMIRIREEIRAVENGTLDKDDNPLKNAPHTAAELVGEWTHPYSREQAVYPVASLIEGKYWPPVGRVDNVFGDRNLVCACPSIESYA