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gata3

Gene
GATA3
Protein
GATA-binding factor 3
Organism
Gallus gallus
Length
444 amino acids
Function
Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes.
Mass
48.197 kDa
Sequence
MEVSTDQPRWVSHHHPAVLNGQHPDSHHPTLGHTYMDPTQYPLAEEVDVLFNIDGQGNPVPPYYGNSVRATVQRYPTAHHGSQVCRPPLLHGSLPWLDGSKALSSHHSASPWNLSPFSKTSIHHSSPGPLSVYPPASSSTLSAGHSSPHLFTFPPTPPKDVSPDPSISTPGSTGSTRQDEKECIKYQVSLADTMKLESSHSRSSMASLGGATSSAHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDNLEDFPKSSSFNPAALSRHMSSISHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

Gene
GATA3
Protein
Trans-acting T-cell-specific transcription factor GATA-3
Organism
Homo sapiens
Length
443 amino acids
Function
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.
Mass
47.916 kDa
Sequence
MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFNIDGQGNHVPPYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

Gene
Gata3
Protein
Trans-acting T-cell-specific transcription factor GATA-3
Organism
Mus musculus
Length
443 amino acids
Function
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.
Mass
47.968 kDa
Sequence
MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLGHSYMEAQYPLTEEVDVLFNIDGQGNHVPSYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALSSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLAAGHSSPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVQLPDSMKLETSHSRGSMTTLGGASSSAHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDALEDFPKSSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSGLSFGPHHPSSMVTAMG

Gene
GATA3
Protein
Trans-acting T-cell-specific transcription factor GATA-3
Organism
Homo sapiens
Length
443 amino acids
Function
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.
Mass
47.916 kDa
Sequence
MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFNIDGQGNHVPPYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

Gene
Gata3
Protein
Trans-acting T-cell-specific transcription factor GATA-3
Organism
Mus musculus
Length
443 amino acids
Function
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.
Mass
47.968 kDa
Sequence
MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLGHSYMEAQYPLTEEVDVLFNIDGQGNHVPSYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALSSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLAAGHSSPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVQLPDSMKLETSHSRGSMTTLGGASSSAHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDALEDFPKSSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSGLSFGPHHPSSMVTAMG

Gene
GATA3
Protein
Trans-acting T-cell-specific transcription factor GATA-3
Organism
Bos taurus
Length
443 amino acids
Function
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses (By similarity).
Mass
47.807 kDa
Sequence
MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLGHSYMDPAQYPLPEEVDVLFNIDGQGNHVPSYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSAGHSSPHLFTFPPTPPKDVSPDPSLSTPGSAGSGRQDEKECIKYQVPLPDSMKLESAHPRGSMATLGGAAASAHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDALEDFPKSSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

Gene
gata3
Protein
Transcription factor GATA-3
Organism
Danio rerio
Length
438 amino acids
Mass
47.59 kDa
Sequence
MEVSPEQHRWVTHHTVGQHPETHHPGLGHSYMDPSQYQLAEDVDVLFNIDGQSNHPYYGNPVRAVQRYPPPPHSSQMCRPSLLHGSLPWLDGGKSIGPHHSTSPWNLGPFPKTSLHHSSPGPLSVYPPASSSSLSAGHSSPHLFTFPPTPPKDVSPDPAISTSGSGSSVRQEDKECIKYQVSLAESMKLDSAHSRSMASIGAGASSAHHPIATYPSYVPDYGPGLFPPSSLIGGSSSSYGSKTRPKTRSSSEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKSHDSMEDFSKSLMEKNSSFSPAALSRHMTSFPPFSHSGHMLTTPTPMHPSSSLPFASHHPSSMVTAMG

Gene
gata3
Protein
Transcription factor GATA-3
Organism
Danio rerio
Length
438 amino acids
Mass
47.59 kDa
Sequence
MEVSPEQHRWVTHHTVGQHPETHHPGLGHSYMDPSQYQLAEDVDVLFNIDGQSNHPYYGNPVRAVQRYPPPPHSSQMCRPSLLHGSLPWLDGGKSIGPHHSTSPWNLGPFPKTSLHHSSPGPLSVYPPASSSSLSAGHSSPHLFTFPPTPPKDVSPDPAISTSGSGSSVRQEDKECIKYQVSLAESMKLDSAHSRSMASIGAGASSAHHPIATYPSYVPDYGPGLFPPSSLIGGSSSSYGSKTRPKTRSSSEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKSHDSMEDFSKSLMEKNSSFSPAALSRHMTSFPPFSHSGHMLTTPTPMHPSSSLPFASHHPSSMVTAMG

Gene
gata3
Protein
GATA-binding factor 3
Organism
Xenopus laevis
Length
435 amino acids
Mass
47.52 kDa
Sequence
MEVSAEQPRWVSHPHHPALLNGQHTDSHHQVHNYMDPSQYPPPEDMDVLFNIDAQGNHVPSYYSNSVRTVPRYPPPHHGSLVCHPSILQSWTDGRKSLGGPHAASAWNLPFTKPSIHHNSPGGLSVYPPASSASLATGHSSPHLFTFPPTPPKDVSPDPSISTSGSTSSSRHEEKECVVSKYQVSLGDTGMKLESLHPRNSMSGIGGVSAHHPITTYPDYYGAGLFQPGSILDGSPTHFSSNARPKTRSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKFHDSLEDYPKSSSFSPAALSRHMSSLSHIPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

Gene
gata3
Protein
GATA-binding factor 3
Organism
Xenopus laevis
Length
435 amino acids
Mass
47.52 kDa
Sequence
MEVSAEQPRWVSHPHHPALLNGQHTDSHHQVHNYMDPSQYPPPEDMDVLFNIDAQGNHVPSYYSNSVRTVPRYPPPHHGSLVCHPSILQSWTDGRKSLGGPHAASAWNLPFTKPSIHHNSPGGLSVYPPASSASLATGHSSPHLFTFPPTPPKDVSPDPSISTSGSTSSSRHEEKECVVSKYQVSLGDTGMKLESLHPRNSMSGIGGVSAHHPITTYPDYYGAGLFQPGSILDGSPTHFSSNARPKTRSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKFHDSLEDYPKSSSFSPAALSRHMSSLSHIPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

Gene
GATA3
Protein
GATA transcription factor 3
Organism
Arabidopsis thaliana
Length
269 amino acids
Function
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes.
Similarity
Belongs to the type IV zinc-finger family. Class A subfamily.
Mass
30.468 kDa
Sequence
MELWTEARALKASLRGESTISLKHHQVIVSEDLSRTSSLPEDFSVECFLDFSEGQKEEEEEVVSVSSSQEQEEQEHDCVFSSQPCIFDQLPSLPDEDVEELEWVSRVVDDCSSPEVSLLLTQTHKTKPSFSRIPVKPRTKRSRNSLTGSRVWPLVSTNHQHAATEQLRKKKQETVLVFQRRCSHCGTNNTPQWRTGPVGPKTLCNACGVRFKSGRLCPEYRPADSPTFSNEIHSNLHRKVLELRKSKELGEETGEASTKSDPVKFGSKW