Protein
5-keto-4-deoxy-D-glucarate aldolase
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Function
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
Similarity
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Sequence
MDNAIFPNKFKAALAAHQVQIGCWCALANPISTEVLGLAGFDWLVLDAEHAPNDVTTLIPQLMALKGSSSAQVVRVPTNEPIIIKRMLDIGFYNFLVPFVETAEQAAQAVASTRYPPEGIRGVSVSHRGNMFGTVPDYFAQSNKNISILVQIESQTGVDNVEAIAATEGVDGVFVGPSDLAAALGHLGNASHPEVQRAIQHIFASAKKHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADAFKK