About Products Protein Database Contact

gap2

Gene
GAP2
Protein
General amino-acid permease GAP2
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
588 amino acids
Function
Amino-acid permease with broad substrate specificity (PubMed:21764911, PubMed:28028545). GAP2 is the only amino-acid permease with very broad substrate specificity, none of the other GAP permeases is able to transport such a variety of amino acids (PubMed:21764911, PubMed:28028545). GAP2 is also able to transport thialysine, and thus probably also lysine (PubMed:21764911). Functions as a sensor via detection of some amino acids including methionine, leading to a rapid activation of trehalase, a downstream target of PKA (PubMed:21764911).
Similarity
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
Mass
63.545 kDa
Sequence
MPEKELDYIRSTDAAGSTEKDGGIYIDAFDKQDNAPPKKGFAKFIDGFRRADAEELGIDPNLSEAEKIAIMTANSPLTRSLKNRHLQMIAIGGSIGTGLFVGSGSSLHTGGPAGLLIAYILIGTMIYCTVMSLGELAVTFPVSGAFVTYNSRFIDPSWGFAMAWNYAMQWLVVLPLELVAAAMTVKYWDAKTNSAAFVVIFYVLIVAINFFGVRGYGEAEFIFSAVKVLAVLGFIILGIVLCAGGGPQGGYIGGKNWYIEGAPFPNGAKGVITVFVNAAFAFAGTELCGLAAAETENPRKSLPKACKQVFWRITLFYVICLTLVGLLVPWNDERLLGSSSADASASPFVISIRNAGIKGLPSVMNVVIMIAVLSVGNSSVYGSSRTLAALAASNQAPKIFGYIDKQGRPLVGIIAQLLVGLLCFLAASDKQGEVFNWLLALSGLSSIFTWGSINVCLIRFRRALAAQGRDTGELVFTSQVGVIGAIWGAFLNTVVLCLQFWIAVWPLHSSPSAEAFFSAYLTVPVVIVFYVGHKLWTKNWQVYICAKDIDIDTGRRELDLDLVKQEVAEEKAYIASLPFYRRVYNAWC

Gene
gap2
Protein
Glyceraldehyde-3-phosphate dehydrogenase-like protein
Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Length
461 amino acids
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
50.082 kDa
Sequence
MIPLIGQLYRNNNVVTSIHGRGLINRSVIAIMKAHRFARHRMADDAELSVHETFPILKAMSELKLGAASVDLGKMVAKFKAEGNGRSIEDFVKAELAEVAGKQNGDAREGTDVVLYGFGRIGRLLARILIEKTGGGDGLRLRAIVVRKGAENDLVKRASLLRRDSVHGPFDGTITIDEENNTLTANGNLIQVIYSNDPASIDYTQYGIKNALLVDNTGKWRDAEGLGQHLKCPGIDRVVLTAPGKGALKNIVHGINHTDIGADDKIISAASCTTNAIVPVLKAVNDQYGIVNGHVETVHSYTNDQNLIDNFHKGSRRGRSAPLNMVITKTGAATAAAKALPVLKGKLTGNAIRVPTPNVSMAILNLNLEKATTREEINEYLRQMAMHSDLQKQIDFVSSQEVVSTDFVGSRHAGVVDAEATICNDNRVVLYVWYDNEFGYSCQVVRVMEDMAGVNPPAFPR

Gene
gap2
Protein
Glyceraldehyde-3-phosphate dehydrogenase 2
Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Length
338 amino acids
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
36.868 kDa
Sequence
MAKAKIAVNGYGTIGKRVADAVRAQDDMEVVGISKTKPNYEAAVAHRLGYDIYAPAANLEAFEKAGMPAAGSIEEMLEKADLVVDCTPGGIGEKNKPIYEKVGIKAIWQGGESHPIAGFSFNAESNYEQAVGRDLTRVVSCNTTALCRAISTIDRELGVNKVRASLSRRAVDPNEIKKGPVDAIVLNPVKLPSHHGPDVRSVLPHINITTAAIKVPTTLMHVHTVNMEVNKDCTAEDVKNIFGSQSRIRLVGQGITSTAEIIEFARDIGRPRHDMWELCIWPESITVTDKELYFFHAVHQESIVVPENVDAIRAMMELESDGAKSIEKTNKAIGLYNK

Gene
gap2
Protein
Glyceraldehyde-3-phosphate dehydrogenase 2
Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length
337 amino acids
Function
Gap2 has a major role in carbon fixation as a component of the Calvin cycle. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
36.876 kDa
Sequence
MIRVAINGFGRIGRNFARCWLGRENSNIELVAVNDTSDPRTNAHLLKYDSMLGKLKNVDITADDNSITVNGKTIKCVSDRNPENLPWKEWEIDLIIESTGVFTSKEGALKHVNAGAKKVLITAPGKNEDGTFVIGVNHHDYDHNVHHIISNASCTTNCLAPIAKVLNDKFGIIKGSMTTTHSYTGDQRLLDASHRDLRRARAAAINIVPTSTGAAKAVALVIPELKGKLNGVALRVPTPNVSMVDFVVQVEKRTITEEVNQALKDASEGPLKGILDYSELQLVSSDYQGTDASSIVDASLTLVMGNDLVKVMAWYDNEWGYSQRVLDLAELVAEKWV

Gene
gap2
Protein
Glyceraldehyde-3-phosphate dehydrogenase 2
Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Length
337 amino acids
Function
Gap2 has a major role in carbon fixation as a component of the Calvin cycle. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NADP. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NADP to NADPH. The reduced NADPH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
36.91 kDa
Sequence
MIRVAINGFGRIGRNFARCWLGRENTNIELVAVNDTSDPRTNAHLLKYDSMLGKLKNVDITADDNSITVNGKTIKCVSDRNPENLPWKEWEIDLIIEATGVFVSKEGATKHINAGAKKVLITAPGKNEDGTFVMGVNHHDYDHNLHNIISNASCTTNCLAPIAKVLNDKFGIIKGSMTTTHSYTGDQRLLDASHRDLRRARAAAINIVPTSTGAAKAVALVIPELKGKLNGVALRVPTPNVSMVDFVVQVEKRTITEEVNQALKDASEGPLKGILDYSELQLVSSDYQGTDASSIVDANLTLVMGNDLVKVMAWYDNEWGYSQRVLDLAELVAEKWV

Gene
gap2
Protein
Glyceraldehyde-3-phosphate dehydrogenase 2
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
337 amino acids
Function
Involved in photosynthetic carbon assimilation. Catalyzes the NAD(P)-dependent oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG). The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. It can use both NADP and NAD.
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
36.512 kDa
Sequence
MTRVAINGFGRIGRNFLRCWLGRTDSQLEVVGINDTSDPRTNAHLLRYDSMLGKLDADISADENSITVNGKTIKCVSDRNPLNLPWAEWNVDLVIEATGVFVTHEGATKHVQAGAKKVLITAPGKGPNIGTYVVGVNAHEYKHEEYEVISNASCTTNCLAPFGKVINDNFGIIKGTMTTTHSYTGDQRILDASHRDLRRARAAAVNIVPTSTGAAKAVALVIPELQGKLNGIALRVPTPNVSVVDLVVQVEKNTIAEQVNGVLKEAANTSLKGVLEYTDLELVSSDFRGTDCSSTVDGSLTMVMGGDMVKVIAWYDNEWGYSQRVVDLAEIVAKNWK

Gene
gap2
Protein
Glyceraldehyde-3-phosphate dehydrogenase 2
Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Length
335 amino acids
Function
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
36.162 kDa
Sequence
MTIRVGINGFGRIGRNYFRALLEQGADIEIVAVNDLGDTATTAHLLKYDTILGRLKAEVTHTADTITVDGKTIKVFSERNPADIPWGELNVDIVIESTGIFTKKADAEKHIAGGAKKVLISAPASDEDITIVLGVNEDKYDPAKHNVISNASCTTNCVAPMAKVLDENFGIVKGLMTTIHAYTNDQRILDFPHKDLRRARAAAENIIPTTTGAAKATALVLPQLKGKMDGISMRVPVPTGSATDLVVEVSREVTKDEVNAAFKKAAEGELQGYLSYTEDPIVSSDIVGDPSSCTFDSAMTMVMEGTSVKILGWYDNEWGYSNRLVDLTVFVGNQL

Gene
gap2
Protein
Glyceraldehyde-3-phosphate dehydrogenase 2
Organism
Streptomyces arenae
Length
334 amino acids
Function
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
35.019 kDa
Sequence
MTVRIGINGFGRIGRNVFRAAAARSSELEIVAVNDLGDVPTMAHLLAYDSILGRFPEEVTAEPGAIRVGDRTIKVLAERDPGALPWGDLGVDIVIESTGIFTDAAKARSHVDGGAKKVIIAAPASGEDFTVVLGVNDGDYDPERHTIISNASCTTNCLGVLAKVLHDAVGIDSGMMTTVHAYTQDQNLQDAPHKDLRRARAAALNIVPTSSGAAKAIGLVLPELAGRLDAFALRVPVPTGSVTDLTVTTRRGTSVEEVKEAYAAAASGPYKGLLSYVDAPLVSTDIVGDPASCVFDAGLTRVSGPQVKVVGWYDNEWGYSNRLIDLATLIGSSL

Gene
GAP2
Protein
Glyceraldehyde-3-phosphate dehydrogenase 2
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
331 amino acids
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
35.546 kDa
Sequence
MVRVAINGFGRIGRLVLRIALSRPNVEVVAINDPFISVDYAAYMFKYDSTHGRFAGEVSHDENSLIIDGKKVLVFQERDPATLPWGEHNVDIAIDSTGVFKELDSAQKHIDAGAKKVVITAPSSTAPMFVVGVNEDKYNGETIVSNASCTTNCLAPLAKVVNNAFGIEEGLMSTIHSITATQKTVDGPSQKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLAKEATYDEIKAVIKKASENELKGILGYTEDAVVSSDFLGDTNSSIFDAAAGIQLSPKFVKLVTWYDNEYGYSTRVVDLVELVAKN

Gene
GAP2
Protein
Glyceraldehyde-3-phosphate dehydrogenase 2
Organism
Kluyveromyces marxianus
Length
331 amino acids
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
35.54 kDa
Sequence
MVRIAINGFGRIGRLVLRIALSRKNIEVVAINDPFITVDYAAYMFKYDSTHGRFDGEVSHDGKSLIIDGKKVLVFQERDPATLPWGAEKIDIAIDSTGIFKELDSAQKHIDAGAKKVVITAPSSTAPMFVVGVNEDKYAGQTIVSNASCTTNCLAPLAKIINNAFGIEEGLMTTVHSITATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLAKPATYEEIKAVVKKASENELKGVMGYTEDAVVSSDFLGDTHSSIFDAAAGIQLSPQFVKLVSWYDNEFGYSTRVVDLVELVAKN

Gene
gap2
Protein
Glyceraldehyde-3-phosphate dehydrogenase 2
Organism
Bacillus cereus
Length
14 amino acids
Function
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
Similarity
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Mass
1.604 kDa
Fragment
single
Sequence
MKQGINGFARRGRL