Protein
Metallothiol transferase FosB 1
Organism
Bacillus anthracis (strain CDC 684 / NRRL 3495)
Function
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.
Similarity
Belongs to the fosfomycin resistance protein family. FosB subfamily.
Sequence
MLKGINHLCFSVSNLEDSITFYEKVLEGELLVRGRKLAYFNICGVWIALNEEIHIPRKEIHQSYTHIAFSVEQKDFERLLQRLEENDVHILQGRERDVRDCESIYFVDPDGHKFEFHSGTLQERLNYYREDKPHMTFY