Function
Component of the phenyllactate dehydratase complex FldABC that is involved in the fermentation of L-phenylalanine via a Stickland reaction. This complex catalyzes the reversible syn-dehydration of (R)-phenyllactate to (E)-cinnamate in two steps, a CoA-transfer from cinnamoyl-CoA to phenyllactate, catalyzed by FldA, followed by the dehydration of phenyllactyl-CoA to cinnamoyl-CoA, catalyzed by FldB and FldC. Requires the activator FldI to initiate catalysis.
Sequence
MSDRNKEVKEKKAKHYLREITAKHYKEALEAKERGEKVGWCASNFPQEIATTLGVKVVYPENHAAAVAARGNGQNMCEHAEAMGFSNDVCGYARVNLAVMDIGHSEDQPIPMPDFVLCCNNICNQMIKWYEHIAKTLDIPMILIDIPYNTENTVSQDRIKYIRAQFDDAIKQLEEITGKKWDENKFEEVMKISQESAKQWLRAASYAKYKPSPFSGFDLFNHMAVAVCARGTQEAADAFKMLADEYEENVKTGKSTYRGEEKQRILFEGIACWPYLRHKLTKLSEYGMNVTATVYAEAFGVIYENMDELMAAYNKVPNSISFENALKMRLNAVTSTNTEGAVIHINRSCKLWSGFLYELARRLEKETGIPVVSFDGDQADPRNFSEAQYDTRIQGLNEVMVAKKEAE