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fesII

Gene
fesII
Protein
Protein FeSII
Organism
Azotobacter vinelandii
Length
122 amino acids
Function
Binds to and protects nitrogenase from irreversible exposure to O(2), in what is known as 'conformational protection' (PubMed:7830548, PubMed:7548055, PubMed:10220344, PubMed:26654855). Shifts nitrogenase into an inactive, O(2)-tolerant state. Exists in 2 states, an open oxidized state that binds and protects nitrogenase, and a closed reduced state that probably does not bind nitrogenase; cooperative oxidation of the 2Fe-2S clusters causes the conformation change (PubMed:26654855). Does not protect nitrogenase with the vanadium-iron subunit, not clear if it protects the iron-only nitrogenase (PubMed:7830548).
Similarity
Belongs to the adrenodoxin/putidaredoxin family.
Mass
13.271 kDa
Sequence
MATIYFSSPLMPHNKKVQAVAGKRSTLLGVAQENGVKIPFECQDGNCGSCLVKITHLDGERIKGMLLTDKERNVLKSVGKLPKSEEERAAVRDLPPTYRLACQTIVTDEDLLVEFTGEPGGA