Protein
Hsp70 nucleotide exchange factor fes-1
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity).
Similarity
Belongs to the FES1 family.
Sequence
MDKNLNQLLKWSIEAQTAANAGQSYHSNGAPTPNNNSGPATGTGAVATSPAPQVTGSGPRPVDPEVLASLFGGPSEAELMKAAMEVITDPSPETTRENKLIAFDNFEQLIENLDNANLLEELSLWSPLISLLDHEDEDMRYHAAWCLGTAVQNNQKTQERLLAMGGVPKLVDLAMKEGESEKVRRKATYALSSAVRNYQPAMDVAADEMHKRGHEVLVNNGTKVDAADMDKVDEVIDVLRNKAKSA