fat-3

Gene

fat-3

Protein

Delta(6)-fatty-acid desaturase fat-3

Organism

Caenorhabditis elegans

Length

443 amino acids

Function

Delta(6) fatty acid desaturase that acts on a range of substrates. Catalyzes the desaturation of linoleic acid (Delta(9,12)-18:2, or C18:2(n-6)) to gamma-linolenic acid (Delta(6,9,12)-18:3, or C18:3(n-6)) (PubMed:11972048, PubMed:9480865). Plays a role in synaptic vesicle recycling by regulating synaptojanin unc-26 localization at synapses (PubMed:18094048).

Similarity

Belongs to the fatty acid desaturase type 1 family.

Mass

51.773 kDa

Sequence

MVVDKNASGLRMKVDGKWLYLSEELVKKHPGGAVIEQYRNSDATHIFHAFHEGSSQAYKQLDLLKKHGEHDEFLEKQLEKRLDKVDINVSAYDVSVAQEKKMVESFEKLRQKLHDDGLMKANETYFLFKAISTLSIMAFAFYLQYLGWYITSACLLALAWQQFGWLTHEFCHQQPTKNRPLNDTISLFFGNFLQGFSRDWWKDKHNTHHAATNVIDHDGDIDLAPLFAFIPGDLCKYKASFEKAILKIVPYQHLYFTAMLPMLRFSWTGQSVQWVFKENQMEYKVYQRNAFWEQATIVGHWAWVFYQLFLLPTWPLRVAYFIISQMGGGLLIAHVVTFNHNSVDKYPANSRILNNFAALQILTTRNMTPSPFIDWLWGGLNYQIEHHLFPTMPRCNLNACMKYVKEWCKENNLPYLVDDYFDGYAMNLQQLKNMAEHIQAKAA

Protein

Delta(6)-fatty-acid desaturase fat-3: fat-3