Protein
ESX-5 secretion-associated protein EspG5
Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
Function
Specific chaperone for cognate PE/PPE proteins. Plays an important role in preventing aggregation of PE/PPE dimers. Required for LipY and PE31/PPE18 secretion.
Similarity
Belongs to the EspG family.
Sequence
MDQQSTRTDITVNVDGFWMLQALLDIRHVAPELRCRPYVSTDSNDWLNEHPGMAVMREQGIVVGDTVNEQVAARMRVLAAPDLEVVALLSRGKLLYGVVDNEDQPPGSRDIPDNEFRVVLARRGQHWVSAVRVGNDITVDDVSVSDSASIAALVIDGLESIHHADPAAINAVNVPLEEMLEATKSWQESGFNVFSGGDLRRMGISASTVAALGQALSDPAAEVAVYARQYRDDAKGPSASVLSLKDGSGGRIALYQQARTAGSGEAWLAICPATPQLVQVGVKTVLDTLPYGEWKTHSRV