About Products Protein Database Contact

ermC

Gene
ermC
Protein
rRNA adenine N-6-methyltransferase
Organism
Staphylococcus aureus
Length
244 amino acids
Function
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Mass
28.861 kDa
Sequence
MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVKRCNFVTAIEIDHKLCKTTENKLVDHDNFQVLNKDILQFKFPKNQSYKIYGNIPYNISTDIIRKIVFDSIANEIYLIVEYGFAKRLLNTKRSLALLLMAEVDISILSMVPREYFHPKPKVNSSLIRLSRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYKLFNK

Gene
ermC
Protein
rRNA adenine N-6-methyltransferase
Organism
Staphylococcus aureus
Length
244 amino acids
Function
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Mass
28.935 kDa
Sequence
MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQVLNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYGFAKRLLNTKRSLALFLMAEVDISILSMVPREYFHPKPRVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYKLFNK

Gene
ermC
Protein
rRNA adenine N-6-methyltransferase
Organism
Staphylococcus aureus
Length
244 amino acids
Function
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Mass
28.873 kDa
Sequence
MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQVLNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYGFAKRLLNTKRSLALLLMAEVDISILSMVPREYFHPKPKVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYKLFNK

Gene
ermC
Protein
23S rRNA methylase leader peptide
Organism
Escherichia coli
Length
31 amino acids
Function
This peptide is involved in the control mechanism of the synthesis of the erythromycin resistance protein.
Mass
3.803 kDa
Sequence
MLVFQMRYQMRYVDKTSTVLKQTKKSDYADK

Gene
ermC
Protein
23S rRNA methylase leader peptide
Organism
Escherichia coli
Length
31 amino acids
Function
This peptide is involved in the control mechanism of the synthesis of the erythromycin resistance protein.
Mass
3.803 kDa
Sequence
MLVFQMRYQMRYVDKTSTVLKQTKKSDYADK

Gene
ermC
Protein
23S rRNA methylase leader peptide
Organism
Enterococcus faecalis
Length
27 amino acids
Function
This peptide is involved in the control mechanism of the synthesis of the erythromycin resistance protein.
Mass
3.162 kDa
Sequence
MLVFQMRNVDKTSTVLKQTKNSDYADK

Gene
ermC
Protein
23S rRNA methylase leader peptide
Organism
Streptococcus pneumoniae
Length
27 amino acids
Function
This peptide is involved in the control mechanism of the synthesis of the erythromycin resistance protein.
Mass
3.162 kDa
Sequence
MLVFQMRNVDKTSTVLKQTKNSDYADK

Gene
ermC
Protein
23S rRNA methylase leader peptide
Organism
Staphylococcus aureus
Length
19 amino acids
Function
This peptide is involved in the control mechanism of the synthesis of the erythromycin resistance protein.
Mass
2.21 kDa
Sequence
MGIFSIFVISTVHYQPNKK