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erg2

Gene
ERG2
Protein
C-8 sterol isomerase
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
241 amino acids
Function
Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
Similarity
Belongs to the ERG2 family.
Mass
26.265 kDa
Sequence
MASHRPRSNKAANGASTSPKRSWIIVSAALVGFCALIAALDSIRSSFYIFDHKAIYKIASTAVANHPGNATAIFDDVLDNLRADPKLAPYINKNHFSDESEWMFNNAGGAMGSMFIIHASVTEYLIFFGTPVGTEGHTGRHTADDYFNILTGNQYAFPAGALKAEHYPAGSVHHLRRGTVKQYMMPEDGCWALELAQGWIPPMLPFGLADVLSSTLDLPTFGITVWITAREMVGNLLIGKF

Gene
erg2
Protein
Protein erg2 homolog
Organism
Dictyostelium discoideum
Length
233 amino acids
Function
May function in lipid transport from the endoplasmic reticulum and be involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. May regulate calcium efflux at the endoplasmic reticulum (By similarity).
Similarity
Belongs to the ERG2 family.
Mass
26.715 kDa
Sequence
MDYFKTLEINNFNDYLNHLIQGNKVVIGTSILGLVIAIFIFIKIKLMRCIELDTKILHECTKKGVGLPIDEAFEAIHKELIKHYPQFITAKRNWLLFNGGGAMGQMCVLHASLSEYLIFYGTPLYSQGHSGRYLMDVYDFMIQGTTKQFFPGKFQSIDFPAGKFSYLPMMVAKGYCCEPNSWMLEYGRGVIPLALPYFLFSSIFVTLDIVPWISAVFYVGREVTKNLLIRRKI

Gene
ERG2
Protein
C-8 sterol isomerase
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
222 amino acids
Function
Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
Similarity
Belongs to the ERG2 family.
Mass
24.896 kDa
Sequence
MKFFPLLLLIGVVGYIMNVLFTTWLPTNYMFDPKTLNEICNSVISKHNAAEGLSTEDLLQDVRDALASHYGDEYINRYVKEEWVFNNAGGAMGQMIILHASVSEYLILFGTAVGTEGHTGVHFADDYFTILHGTQIAALPYATEAEVYTPGMTHHLKKGYAKQYSMPGGSFALELAQGWIPCMLPFGFLDTFSSTLDLYTLYRTVYLTARDMGKNLLQNKKF

Gene
ERG2
Protein
C-8 sterol isomerase
Organism
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Length
221 amino acids
Function
Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
Similarity
Belongs to the ERG2 family.
Mass
24.721 kDa
Sequence
MSSPISGFLRFVAVLLAVVSPLVYLAEQRLESFYVFDHKHLHELSTQAIAQHGNNTRAIVGHIVDELRARPETTKYISVQEEWVFNNAGGAMGGMYIIHASVTEYLIIFGTAIGTEGHTGRHTADDYFNILTGEQWAYVPGEYEPEVYPAGSVHHLRRGTVKQYKMPEGCFALEYARGWIPPMLFFGFADGLSSTLDFPTLWQTTVVTGREMLGNLMLGKF

Gene
erg2
Protein
C-8 sterol isomerase erg2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
219 amino acids
Function
Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols. Involved in the biosynthesis or ergosterol which is important for plasma membrane structure and function and for localization of plasma membrane proteins.
Similarity
Belongs to the ERG2 family.
Mass
24.671 kDa
Sequence
MKLTKFLTVFIPFIAGLIYYIQKYHLRSFYQFDPAKLQELSKQSIALYANDTKALLYDLSDRLVAEYGDLITPVNQDEWVHNNAGGAMGTMFILHASFSEYLIFFGTPIGTEGHSGVHMADDYFTILRGRQLAASANDLEARVYLPGDQHVHPWGHTAQYSMPSGEPCFALELAQGWIVSMLPFGFMDGLFSTIDFGTLYKTVYFTAGRMLKSVLMGKF