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ereA

Gene
ereA
Protein
Erythromycin esterase type I
Organism
Escherichia coli
Length
406 amino acids
Function
This enzyme confers resistance to erythromycin through inactivation by hydrolyzing the lactone ring of the antibiotic.
Mass
44.783 kDa
Sequence
MTWRTTRTLLQPQKLDFNEFEILTSVIEGARIVGIGEGAHFVAEFSLARASLIRYLVERHEFNAIGLECGAIQASRLSEWLNSTAGAHELERFSDTLTFSVYGSVLIWLKSYLRESGRKLQLVGIDLPNTLNPRDDLAQLAEIIQLIDHLMKPHVDMLTHLLASIDGQSAVISSAKWGELETARQEKAISGVTRLKLRLASLAPVLKKHVNSDLFRKASDRIESIEYTLETLRIMKTFFDGTSLEGDTSVRDSYMAGVVDGMVRANPDVKIILLAHNNHLQKTPVSFSGELTAVPMGQHLAERVNYRAIAFTHLGPTVPEMHFPSPKSPLGFSVVTTPADAIREDSMEQYVIDACGTENSCLTLTDAPMEAKRMRSQSASVETKLSEAFDAIVCVTSAGKDSLVAL
Protein
Erythromycin esterase type I: ereA

Gene
ereA
Protein
Erythromycin esterase type I
Organism
Escherichia coli
Length
406 amino acids
Function
This enzyme confers resistance to erythromycin through inactivation by hydrolyzing the lactone ring of the antibiotic.
Mass
44.783 kDa
Sequence
MTWRTTRTLLQPQKLDFNEFEILTSVIEGARIVGIGEGAHFVAEFSLARASLIRYLVERHEFNAIGLECGAIQASRLSEWLNSTAGAHELERFSDTLTFSVYGSVLIWLKSYLRESGRKLQLVGIDLPNTLNPRDDLAQLAEIIQLIDHLMKPHVDMLTHLLASIDGQSAVISSAKWGELETARQEKAISGVTRLKLRLASLAPVLKKHVNSDLFRKASDRIESIEYTLETLRIMKTFFDGTSLEGDTSVRDSYMAGVVDGMVRANPDVKIILLAHNNHLQKTPVSFSGELTAVPMGQHLAERVNYRAIAFTHLGPTVPEMHFPSPKSPLGFSVVTTPADAIREDSMEQYVIDACGTENSCLTLTDAPMEAKRMRSQSASVETKLSEAFDAIVCVTSAGKDSLVAL
Protein
Erythromycin esterase type I: ereA