enpp4

Bis(5'-adenosyl)-triphosphatase enpp4

459 amino acids

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

51.603 kDa

MQISAYLCALIACCGLTLSAPTANNKSSSEAPPLLLVSFDGFRADYLNKYSFPNLEKFFSDGVLVHELTNVFTTKTFPNHYSLVTGLYAESHGMLASIMYDPVAKKHFSIKNDSDPFWWDEATPIWVSVEESGYHAASAMWPGSDVNIQNHTLKYTFKYDSRVSFKERLGNITQWMTTDKSLKFASLYWEEPDFSGHTYGPDNTTEMARVLKEVDGHVGYLMEELDRMELWGKINVIITSDHGMAQCSEERIIRLDDCVSPSSYTLVDLTPVAAIIPLEDKTTVYNNLSSCHVHLKAYMKNDVPDRLHYKNNERIQPIILVADEGWTIVKNGRLPRLGDHGYDNTLPSMHPFLAAHGPAFRKGYKMSSFNSVDLYPLMCHLIGIPPKANNGSFAHVRCTLVNEQCGELALAVGLVMGVLIILTTFTCLFKLMKNRNVSSPRPFARLELDDDGDDEPLLE

Enpp4

Bis(5'-adenosyl)-triphosphatase enpp4

456 amino acids

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

51.611 kDa

MFNMKILVIPLFWGLVTGYKGNSSDSSAPRLLLVSFDGFRADYLKSYDLPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDSVTKKHFSESNDKDPFWWNGAEPIWVTNQLQENRSSAAAMWPGTDVPIHNITASYFMNYSSSVSFKERLGNVTTWLSSSNPPVTFAALYWEEPDVSGHKYGPEDKENMRRVLKEVDDLIGDIVLKLKVLGLWDSLNVIITSDHGMAQCSKNRLIDLDSCIDRSNYSVIDLTPVAAILPKINVTEVYDKLKRCNPHMNVYLKEAIPNRFYYQHSSRIQPIILVAEEGWTITLNKSSFKLGDHGYDNSLPSMHPFLAAHGPAFRKGYRQSTINTVDIYPMMCHILGLKPHPNNGTLSHTKCLLVDQWCINLPEAIGIVVSALLVLTMLTGLMIFMRSRASTSRPFSRLQLQEDDDDPLID

ENPP4

Bis(5'-adenosyl)-triphosphatase ENPP4

453 amino acids

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

51.165 kDa

MKLLLMLLFSGLMTGCRGNSSSASPPKLLLVSFDGFRADYLQNYEFPHLQNFIKEGVLVEQVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDVNTKKHFSDHNDKDPFWWNEAVPIWVTNQLQDNRSSAAAMWPGTDVPIHNSTPSYFMNYSPSVSFRERLGNVTTWLSSSNPPVTFATLYWEEPDASGHKYGPEDKENMRRVLEEIDEHIGELVHRLKVLGLWESLNVIITSDHGMTQCSKDRVINLDGCLDPSYYTLIDLTPVAAILPKINKTKVYSKLKVCDPHMNVYLKEDIPARFHYQHSDRIQPIILVADEGWTIVLNKSSLKLGDHGYDNSLPSMNPFLAAHGPAFHKGYKHSSINTVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCINLPEAIGIVIGALLVLTTLTCLIIIMQNRVSGPRPFSRLQLQEDDDDPLIG

ENPP4

Bis(5'-adenosyl)-triphosphatase ENPP4

453 amino acids

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

51.641 kDa

MKLLVILLFSGLITGFRSDSSSSLPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVPIHDTISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLSPVAAILPKINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQKLGDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCINLPEAIAIVIGSLLVLTMLTCLIIIMQNRLSVPRPFSRLQLQEDDDDPLIG

enpp4

Bis(5'-adenosyl)-triphosphatase enpp4

452 amino acids

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

51.497 kDa

MLGRAFIVAVLYCATFCKADKPTNSSTPRLIILSFDGFRADYLTRFPMPNLDEFMKEGVQVEEVKNVFITKTFPNHYSLVTGLYAESHGIVANHMYDNDTRQVFHMNDSNSKWWDEATPIWVTNQKQGHKSGCAMWPGCNVPMHNVTLNASLNYNPNVTFTERVNNVTMWLTRPNDPINFATIYWEEPDASGHRFGPDDHDNMAKVLKEVDEHVGYLMSELKKAKLWDTVNVIITSDHGMAQCSKDRIIKLNDCIGPGNYTLVDDNPVAAILPLSDTQLVYDLLRNCHPHMKVYRKEEIPERWHYKHNSRIQPLLLVADEGWMITQNHSISMLGDHGYDNDLHSMHPFLAAHGPAFRKGYRMRTINSVDIYPLMCHILGITGLPNNGTLKDIKCLLVNQCYIQIPEAIGIVIGAIMVLTTLTCIIVMLKKKMPSTRQFSRLQFQDDDDPLIG

enpp4

Bis(5'-adenosyl)-triphosphatase enpp4

452 amino acids

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

51.497 kDa

MLGRAFIVAVLYCATFCKADKPTNSSTPRLIILSFDGFRADYLTRFPMPNLDEFMKEGVQVEEVKNVFITKTFPNHYSLVTGLYAESHGIVANHMYDNDTRQVFHMNDSNSKWWDEATPIWVTNQKQGHKSGCAMWPGCNVPMHNVTLNASLNYNPNVTFTERVNNVTMWLTRPNDPINFATIYWEEPDASGHRFGPDDHDNMAKVLKEVDEHVGYLMSELKKAKLWDTVNVIITSDHGMAQCSKDRIIKLNDCIGPGNYTLVDDNPVAAILPLSDTQLVYDLLRNCHPHMKVYRKEEIPERWHYKHNSRIQPLLLVADEGWMITQNHSISMLGDHGYDNDLHSMHPFLAAHGPAFRKGYRMRTINSVDIYPLMCHILGITGLPNNGTLKDIKCLLVNQCYIQIPEAIGIVIGAIMVLTTLTCIIVMLKKKMPSTRQFSRLQFQDDDDPLIG

ENPP4

Bis(5'-adenosyl)-triphosphatase ENPP4

452 amino acids

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

51.561 kDa

MKLLVILLFSGLITGFRSDSSSSLPPKLLLVSFDGFRADYLNNYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVPIHNTISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQKLKMLGLWENLNVIITSDHGMTQCSQDRLINLDVCIDHSYYTLIDLSPVAAILPKINRTEVYNRLKNCSSHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQKCDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCINLPEAIAIVIGSLLVLTMLTCLIIIMQNRLSVPRPFSRLQLQEDDDDPLIG

enpp4

Bis(5'-adenosyl)-triphosphatase enpp4

452 amino acids

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

51.312 kDa

MFGRVFIVAVLYCITICKGEDPTNSSTPKLILLSFDGFRADYLTRFPMPNLQEFMKEGVEVEEVKNVFITKTFPNHYSLVTGLYAESHGIVANRMYDADTKQVFHMNDSHSKWWDEATPIWLTNQKQGHRSGCAMWPGSDVSIHNTTPSDFLYYNHTVSFAQRVNHITTWLTRPNDSINFAAIYWEEPDASGHRYGPDDYGNMSGVLKEVDKNVGYLMSELKKANLWDTVNVIITSDHGMAQCSNDRIIKLNDCIGPGNYTLVDDNPVASILPISDTKNVYDLLRNCHPHMKVYMKEEIPDRWHYKHNSRIQPLLLVADEGWMITQNESISMLGDHGYDNDLHSMHPFLAAHGPAFRKSYKMRTINNVDVYPMMCLILGITGQPNNGTLSNTKCLLANQWCIQVSEAIGIVIGAIMVLTTLTCIIIMLKKKMPSARPFSRLQFQDDDDPLIG