eif3a

Eukaryotic translation initiation factor 3 subunit A

1424 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

168.5 kDa

MPVYFQRPENALKRANEFLEVGKKQPALDVLYDVIKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKLAEERTESAKESSQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSKVERLYHDIAQQAFKFCLLYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFALSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLSPEEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQSPPNRVGLIKDMVRFNALQHVVPEVKELYNWLEVDFHPLKLCTRVTKVLDWIKEQAEKEPELQQYVPQLQSNTVLRLLQQVAQIYQTIEFSRLSSLLPFVDAFLLERAIVDAARHCNLQVRIDHTSRTLSFGSDLNYSTREDAPVGPFLQNMPSEHIRNQLTAMSTVLSKAVATIKPAHVLQEKEEQHQIAISAYQKNSRKEHQRILTRRQTIEERKERLENLNIQREKEEHEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTEFGAKAFKDIDIENLEELDPDFIMAKQVEQLEKEKRELQDRLKNQEKKIDYFERAKRLEEIPLLKKAYDEQRISDMELWEQQEEERISTLLVEREKAVEHKNRMSRMLEDRDSFVSNLKASRQSVYDAKLKQFQERLAEEKRVRLEERKRQRKEERRISYYRDKEEEEQRLIEEQLKQEREDREKIENEKREAEQREYQERLKKLEEQERKKRLRELEIEEREKKRDEERRGPDDSFRKQDTPSRWGDREESGWRRGADPDERKQAPPERDWRSGGQDSKPVKDEDREGDEDSVLRKDEEQVARGDGDEERAASWRGTDDRGPKRSVEEDGGPRRGFNDEPGPRRGFEDDQGPRRGLDEDRGPRRGLDEDRGPRRGLDEDRGPRRGLDEDRGPRRGLDEDRGPRRGLDEDRGPRRGLDEDRGPRRGFDEDRGPRRGFDEDRGPRRDFDEDRGPRRGFDEDRGPRRGFDEDRGPRRGFDEDRGPRRGFDDDRGPRRGFDDDRGPRRGFEDDRGPRRGFEDDRGPRRGFEDDRGPRRGFDEDRTPRRGFEDDRGPRRGMDEERVSWRGGAEEDRGPRRGAEEDRGPRRGAEEDRGPRRGAEEDRGPRRGAEEDRGQTPWKPVVTSRPASGGWREREKAREDSWGPSHDSKPPEERDWSKRGEDGEKDSERDRRPVREESAWRRGGDDNVTPRKVSPGDKSTEDRKEPSDVRRAAPKTDEPSQWRQGEQKDSQQEERGTPRRVAAADREKPSWRTEKKEEKDAPRRPKLEEDEDGWTTVRR

eif3a

Eukaryotic translation initiation factor 3 subunit A

1391 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

164.997 kDa

MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVIKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKLAEERTEAAKESSQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSKVERLYHDIAQQAFKFCLLYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFALSKKPPKPQLMANYYNKVSTVFWKSGNTLFHASTLHRLYHLSREMRKNLTQEEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIILEKQRRLATLLGLQAPPTRVGLINDMVRFNMLQYVVPEVKELYNWLEMDFHPLKLCTRVTKVLDWVKEQAEKEPELQQYVPQLQSNTILRLLQQVAQLYQTIEFSRLASLVPFVDAFLLERAIVDAARHCDLQVRIDHSSRTLSFGSDLNYSTREDAPFGPFLQNMPSEQIRNQLTAMSCVLSKAVGAIKPAHVLQEKEEQHQIAITAYQKNSRKEHQRILARRQTIEERKERLENLNIQREKEEMEQKEAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIENLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLLKKAYEEQRINDMELWELQEEERISTLLLEREKAVEHKNRMSRMVEDKELFVSKLKASRQSLYEAKLKQFQERLAEEKAARLEERKRERKEERRVNYYRDKEEEEERLREEQLKQEREEQEKVENEKREAEQRDYQERLKKLEEQERKKRQRELEIEERERKREEERRGGDDTFRKDSSRWGEREESGWRRGADPDERKQVPPERDWRRGGPDSKPVINEDASNREEDENAALRKDEEQVSSRAFEEKVSLPDADEEKGGSWRDEDRGPKRGLEEDRGPRRGIDDAGPRRGFEEDRGPRRGIEDDRAPRRGFDDDRGPRRGFDDDRGPRRGFDEDRGPRRGIDDDRGPRRGFDEDRTPRRGFDDDRGPRRGFDDDRGPRRGFDEDRGPRRGFEDDRGPRRGFEDDRGPRRGFEDDRGPRRGFEDDRGPRRGFEDDRGPRRGFDEDRGPRRGFEDDRGPRRGFDEDRTPRRGFDDDRGPRRGLDEDRGSWRGGDDVPRRGADDDRGPRRGADDDRGPRRGEDRDQTPWKPMAASRPGGWREREKAREDSWGPPRDSQAPEEREWSRQGEDSEKDSERDRRPVREESAWRRGGDNSETPRKPSPGDSDRKDDSDKKRPPKTDEANPWRRGEDKDSREEERGTPRRAPAADREKSAWRTEKKEEKDTPRRIKPETDEDGWTTVRR

EIF3A

Eukaryotic translation initiation factor 3 subunit A

1382 amino acids

(Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).

Belongs to the eIF-3 subunit A family.

166.569 kDa

MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVRFNVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR

Eif3a

Eukaryotic translation initiation factor 3 subunit A

1354 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

Belongs to the eIF-3 subunit A family.

163.196 kDa

MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKLAEEKTEAAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVRFNVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVAQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYIKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRVKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERKITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGEDPLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRETRDDERPHRRDEDRLRRLGGDDEERESSLRPDDDRIPRRGLDDDRGPRRGPDEDRFSRRGTDDDRPSWRNADDDRPPRRIGDDDRGSWRHTDDDRPPRRGLDDDRPPRRGLDDERGSWRTAEEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGMDDDRGPRRGLDDDRGPWRNAAEDRISRRGADDDRGPWRNMDDDRVPRRGDDARPGPWRPFVKPGGWREKEKAREESWGPPRESRPPEEREWDRDKEKDRDNQDREENDKDLERDRDRERDGDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRDRDDRRDLRDLRDRRDLRDDRDRRGPPLRSEREEASSWRRTDDRKDDRTEERDPPRRVPPPTLSRERERERDREGEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR

Eif3a

Eukaryotic translation initiation factor 3 subunit A

1344 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

Belongs to the eIF-3 subunit A family.

161.936 kDa

MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKLAEEKTEAAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQEEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVRFSVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVAQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPVGPHLQSMPSEQIRNQLTAMSSVLAKALEVIRPAHILQEKEEQHQLAVNAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRVKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHSRLEDRKRQRKEERKITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDDPLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRETRDDERPHRRDEDRLRRLGGDDEERESSLRPDDDRIPRRGLDDDRGPRRGPDEDRFSRRGTDDDRPSWRNADDDRPPRRIGDDDRGSWRHTDDDRPPRRGLDDERGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGMDDDRGPRRGLDDDRGPWRNAAEDRISRRGADDDRGPWRNMDDDRVPRRGDDARPGPWRPFVKPGGWREKEKAREESWGPPRESRPSEEREWDRDKEKDRDNQDREENDKDLERDRDRERDGDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDREDRRRDRDDRRDLRDLRDRRDLRDDRDRRGPPLRSEREEASSWRRTDDRKDDRTEERDPPRRVPPPALSRDREREREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR

eif3a

Eukaryotic translation initiation factor 3 subunit A

1267 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

151.292 kDa

MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVIKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKLAEEKTETAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSKVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLGQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFALSKKPPKPQLMANYYNKVSTVFWKSGNALFHSCTLHRLYHLSREMRKNLTQEEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKHRRLATLLGLQSPPTRQSLINDMVRFNLLQYVVPEVKELYNWLEVDFHPLKLCGRVTKVLNWVRDQAEKESDLQQYVPHLQNNTILRLLQQVAQIYQSIEFSRLASLVPFVDAFQLERSIVDAARHCDLQVRIDHSSRTLSFGSDLNYSTKEDSPVGPFLQNMPSEQIRNQLTAMSSSLAKAIQVIKPASILQDHEEQRQQAITAYLKNARKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERIMQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKKAYEEQRIKDMELWELQEEERITNMKMEREKALEHKQRMSRMMEDKENFLSKIKAARSFIYEEKLKQFQERLVEERKKRLEERKKQRKEDRRKAFYHQKEEEAQRIREEQLKKEREERERLEQEQREEEEREYQERLRKLEEQERKQRARQQEIEERERRKEEERRAPEEKPNKEWAEREESGWRKRGEGESEWRRPVPDRDWRQEGREGREEPDREDRDLPFRRGGESARRGASDEKGLRRGCDDDRGPRRGGDDERPPRRGFDDDRGTRRGFDDDRGQRRGDDDRGPRRGMDDDRGPRRPIDDDRGPRRSDDDRGPRRGFDDDRGPRRGMDEPRGPRRGADDDWGPRRGGDDERGGRRGMDDSGPRRGEDSRPWKPLGRPGAGGWREREKAREESWGPPRDSGHDDDGGERDGDDQREGERFRERRSAREEGSAWRRGGGGGGGGEEQSSWRDSRREDFDREDRRERRDMRERRDDRERDIRGPQRDQDEGGSWRRGGEERREERKEERDAPPRPRERDRDSGEKSTWRSDKDKENPRRTKNETDDDGWTTVRR

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1173 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

136.774 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDIIETGPTETNLLSPYIQSLKDVTIMRLIRQISQVYESIEFKRLLELATFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRTQMVHHYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLELEQEERERKRHQNEIQAIKEKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQRERKELQSKLKSQEKKIDYYERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVSQQERLKRMYPDRDEFLEALKKERASLYVEKLKKFEIALEAERKKRLADRVIRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRDRLAREVAVERERSDKERDTWRPRGGDRPSAAAAGGGGGAGEWRRAAAPIGDRNERAGDRIERGGERMERGGDRMERGGDRMERGGERTERGGDRMDRGGERMDRGGERGERGADRDRERRDNEGADSSWRVRREPDSQRGAGVKDASGSAAPPSRDDKWRRGGDRDRDRDRDFRNDGPRRDRDDRDDRDRGGFRRNDGPRRNDDAAPRETGGNWRDAPRQSDRDNRRPAGDRRDREVRGGDLRGPESRAPKEGGPSGGTGTAAGGGGNWRTAPGPRDEPAPKRDQPQDKGKFSLTPVQL

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1141 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

133.915 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGPENALLTPYIQSLKDVTIMRLIRQISQVYESIKFQRLLQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRNQMVSQYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERMDAVAQQERLKRMYPDRDEFLEALKKERASLYVEKLKKFEAALEAERKKRLADRIVRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRDRLSRELASERERTEKERDTWRPRGGDRPSASAGGSSEWRRAAPAVSERNDRGGERIERGGDRVERGGERIERGGERIERGGDRDRKDNEGADSSWRVRREPDTQRAAAPKDSGAPQSRDDKWRRGGERDRDFRNDGARRDRDDGPRRDRDDGPRRDRDDERGGFRRNDGPRRTDEPQRESGGNWRDAPRHADRENRRPAGERRDRDVRETRGDQRGSAPKEAASGGGGGNWRNAPATREEKPAAKRDQAQEKENKAGDDGEWTSVKRR

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1141 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

133.926 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGPENALLTPYIQSLKDVTIMRLIRQISQVYESIKFQRLLQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRNQMVSQYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVAQQERLKRMYPDRDEFLEALKKERASLYVEKLKKFEAALEAERKKRLADRIVRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRDRLSRELASERERTEKERDTWRPRGGDRPSASAGGSSEWRRAAPAVSERNDRGGERIERGGDRVERGGERIERGGERIERGGDRDRKDNEGADSSWRVRREPDTQRAAAPKDSGAPQSRDDKWRRGGERDRDFRNDGARRDRDDGPRRDRDDGPRRDRDDERGGFRRNDGPRRTDEPQRETGGNWRDAPRHADRENRRPAGERRDRDVRETRGDQRGSAPKEAASGGGGGNWRNAPATREEKPAAKRDQAQEKENKAGDDGEWTSVKRR

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1140 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

133.351 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEIDFNPLNLCKRIQSIVDIIEGGPAESNLLTPYIQSLKDVTIMRLIRQISQVYESIEFKRLLELASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPSLQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRTQMVHHYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRENEELQREAKELQSKLKSQEKKVDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVSQQERLKRMYPDRDEYLDALKKERASLYVEKLKKFEIALEVERKKRLADRIVRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRERLAREVAVERERSEKERDTWRPRGGDRPSAPAGGAGEWRRAAPPAGERNDRGAERSERGGDRNERGGDRIERGGDRIERGGERAERGGDRDRKDDGGADSSWRVRREPDSQRAAGAKDAGGAPASRDDKWRRGGDRERDRDFRNDGPRRDRDDRDDRDRGGFRRNDGPRRNDEPQRETGGNWRDAPRQSDRDNRRPGGERRDRDGRDVRGDQRGPASKEAGGGGGGGNWRTAPAPRDEKPAAKRDQPQDKENKGGDDGEWTSVKRR

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1140 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

133.88 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGPENALLTPYIQSLKDVTIMRLIRQISQVYESIKFQRLLQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRNQMVNHYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVAQQERLKRMYPDRDEFLEALKKERASLYVEKLKKFEAALEAERKKRLADRIIRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRDRLSRELASERERTEKDRDTWRPRGGDRPSASNGGSSEWRRAAPAASERNDRGGERIERGGERIERGGERLERGGERIERGGDRDRKDNEGADSSWRVRREPDSQRAAAPKDSGAPQSRDDKWRRGGERDRDFRIDGARRDRDDGPRRDRDDGPRRDRDDERGGFRRADGARRTDEPQRETGGNWRDAPRHADRETRRPAERRDRDVRETRGDQRGSAPKEAASGGVGGNWRTAPATREEKPAAKRDQAQEKENKAGDDGEWTSVKRR

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1140 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

133.443 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCETLYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAILLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCQRIQSVVDTIESGPAETSLLTPYIQSLKDVTIMRLIRQISQVYESIEFKRLLELASFCNVFELEKLLVESVRHNDMQIRIDHQKHCIYFGTDLTESQREYRPDGPTLQSMPSEQIRSQLVNMSTVLTRAVSIVYPDREREQRAKLRTQMVHHYHEIKDREHQRILQRQKIIEDRKEFIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRENEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLTEKQVKDKEFWEATEQTRIENAITERKDAVSQQERLKRMYPDRDEYLEALKKERASLYLEKVEKFEIALEVERKKRLADRVIRRREERRQAHLREKEEERLRKEEEIRMAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRDRLAREVAVERERSDKERDTWRPRGDRPEGRPSAAAGGGGASEWRRPAPTADRADRDRGADRDRGADRDRGADRDRGADRERGADRDRKDNEAGGASDSWRVRREPDSQRNAAPKDGGGSSGGAQPSRDDKWRRGGDRERDRDFRNDGQGPRRGGDREDDRDRGGFRRNDGPRRNEEQQRETGGNWRDAPRQSDNRDNRRPAGGDRRDRDRDVRGAGPKEGGGGGGGNWRTAPAPRDEKPTTKQRDQPQDKENKAGDDGEWTSVKRR

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1138 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

133.726 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMAMSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPNLVSDEFRNLYNWLEVDFNPLNLCKRIQSIVDTIESSETENTLLTPYIQSLKDVTIMRLIRQISQVYESIEFKRLLELAPFCNIFELEKLLVESVRHNDMQIRIDHQRNSIYFGTDLTESQREYRPDGPTLQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRTQMVQHYHEIKDREHQRILQRQKIIEDRKEFIEKQNNAREEEEARRHEEESRKAKLAEQKRLEQEQEERERKRHENEIQAIKEKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAMRESEELQRERKELQSKLKSQEKKIDYFERAKRIEEIPLFEKYLAEKNVKDKEFWEATEQTRIENAIAERKDAVSQQDRLKRMYPDRDEYLEALKKERASLYVEKLKKFDIALAEERKKRLADRVVRRREERRQAYLRAKEEERFRKEEEIRHAREAEERAAAEARRLEREAEDEKRRQQYEKQRAKEEEAERKIQEDRERLAREVAVERERSEKERDVWRPRADRVERPSAAPAGGASEWRRNAPPTDRNERTDRGDRNDRNDRNDRNDRNDRNDRNDRNDRPERAERKENDGGADSSWRVRREPESQRGTGAGMDRSERGGGGAPSGRDDKWRRGGDRSERLGGDRDRDSFRRNDGPRRDDDRGGFRRDDQPQRETGSNWRDSPRQNDRDNRRTTGERRDVRGAGPKEGGGGVSGGGAGGGGGNWRTAPSPREEKAPPKREQAQDKENKAGDDGEWTSVKRR

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1137 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

133.645 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFHFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYRAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGPENALLTPYIQSLKDVTIMRLIRQISQVYESIEFQRLMQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRTQMVNHYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVGQQERLKRMYPDRDEFLDALKKERASLYVEKLKKFEAALEAERKKRLADRIIRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRERLARELASERERTEKERDTWRPRGGDRPSAPSGGSGEWRRGAPTVNNERGIERGGDRIERGGDRIERGGERIERGGDRDRKDNEGADSSWRVRREPDSQRAAAPKDSGAPQSRDEKWRRGGERDRDFRNDGARRDRDDGPRRDRDDGPRRDRDDERSGFRRNDGPRRTEEPQRETGGNWRDAPRHADRENRRTAGGERRDRDVRETRGDQRGPAPKEAVSSGGGGNWRTTPAAREEKPATKRDQPQEKENKAADDGEWTSVKRR

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1135 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

133.539 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGSENALLTPYIQSLKDVTIMRLIRQISQVYESIQFQRLLQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRTQMVNHYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVGQQERLKRMYPDRDEFLEALKKERASLYVEKLRKFEAALEAERKKRLADRIIRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREADDEKRRAQYEKQRAKEEEAERKIKEDRERLARDLASERERTEKERDTWRPRGGDRPSAPAVGSGEWRRAAPTASERNERGGERIERGGDRIERGGERIERGGDRDRDRKDNEGADSSWRVRREPDSQRAAAPKDSNAQQSRDDKWRRGGERDRDFRNDGPRRDRDDGPRRERDDGPRRDRDDERGFRRNDGPRRTEEPQRETGGNWRDAPRNADRENRRPAGERRDRDVRETRGDQRGSAPKEASSGGGGGNWRTAPAAREEKPASKRDQPQEKENKAADDGEWTSVKRR

eIF3a

Eukaryotic translation initiation factor 3 subunit A

1129 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

133.033 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMAMSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPNLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDTIEASETENTLLTPYIQSLKDVTIMRLIRQISQVYESIEFKRLLELAPFCNIFELEKLLVESVRHNDMQIRIDHQRNSIYFGTDLTESQREYRPDGPTLQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRSQMVQHYHEIKDREHQRILQRQKIIEDRKEFIEKQNNAREEEEARRHEEESRKAKLAEQKRLEQEQEERERKRHENEIQAIKEKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAMRESEELQRERKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKNVKDKEFWEATEATRIENAIAERKDAVSQQERLKRMYPDRDEFLEALKKERASLFVEKLKKFEIALAEERKKRLAERVVRRREERRQAYLRAKEEERFRKEEEIRLAREAEERAAAEARRLEREAEDEKRRQQYEKQRAKEEEAERKIQEDRERLAREVAVERERSEKERDVWRPRGDRSERPSAAPAGGASEWRRNAPTSDRNDRNDRNERNDRSDRNDRNDRSERIERSDRNDRPERKDTDGGADSSWRVRREPVEPQRERGGGAGGGPSGRDDKWRRGGDRSERLGGDRDRDRDRDSFRRNDGPRRDDDRGGFRRDDQPQRDTGSNWRDSPRQNDRDNRDNRRPAGDRRDIRGAGPKEGGGGGGGGNWRTAPSPRDEKPPVKRDQPQDKENKAGDDGEWTSVKRR

eif3a

Eukaryotic translation initiation factor 3 subunit A

1059 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

120.243 kDa

MPPPPHQKPENVLKRAHELIGVNQAPAALTLLHEHITSKRSRNVPIASLEPVMLLLVELSVEQKKGKLAKDALYQYKNIAQNTNVATIELVLKKFIELAAEKVTAAQAKADEVQSSIEATTSNIDDLEASETPESILLATVSGEQSRDRTDRAIVTPWLKFLWEAYRTVLDILRNNARLEVLYQSTAMQAFDFCLKYTRKTEFRRLCELLRNHVQTAAKYSAQMHAINLNDPDTLQRHLETRFQQLNVAVELELWQEAFRSVEDIHTLLSLSKRPAKNVMMANYYEKLTRIFLVGENYLFHAAAWARYYNLLRQSAALIASGHSKKADNPACSDADLQRAATFVILSALSIPVISTSRSRGAMVDFDEARKNKNSRLTHLLGMAQAPTRAGLFRDALSKSLLRRAQPQIRDLYNILEVDFHPLSICQKISPILAEIGADAEMQKYILPLQQVILTRLFQQLSQVYETVDLEFVESLAQFPEPFQVTRGTIEKFIMNGNKKGDLAIRMDHATGVLSFDADVFSSAKAVHAGSSAGSAESETGSVQRLQSTPSQIVRSQLTRLAEALYTTCRYIDPSFNEARIKARDEALARAKAGAEKEHQEVLARKEIIQTRKDKASEAQAQKEKENARKKLLQEQALQQAEAARLAEEQKLREAKRLANEREQIKRKEVEALLKDMKLEELQGEDIETLDSNKIRMIKLQQLEREKNSVAEKLRITGKRLDHLERAFRKEEAKKLPEDYAKQRERDLAAYERTKAQTLKEAELKHKADVELKHRLTRLMPFYESFRSDLHERRRDEFEKRRRDAEREMEKQINARRKEAREKRIREKREREERERQLREAEERAAREKEEERKRLEARREELQRLKEEKEKEREKLREIAARQQQREEEAMARRKAEKEKLAATPSAYRPPAAAERTEAAAPPRIALAGNRPSWREREAAKAASGETAAPAPAAAEPVAERPRAAAPPAERTEAAAPPRLALAGNRPSWREREAAKAASGGGNAAAVPERSAPPLRAAAPQRAGSGRPENDRDVPPAEPLKASGAPGKYVPKWRREGA

eif3A

Eukaryotic translation initiation factor 3 subunit A

1030 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

120.076 kDa

MSTQQALAQANEHALSQANDLIKVGSKLRALSVLRDLLSDRSQWHSSLEQIMSLYVSLCAEQLDYQSLRDGIHHFKVSIMSQKEFSIVPLENIFKEIITPIEQKVDELKEKIEKENQENPLVEQNEISLIDPQQTLLFSYMKYLFEAYKAMIEVLTRQNTKFEHTKFDHSKFDSTLLKISTQALNYCSKYQRKPDFMVLTELFRSSIEQLFKVPSLDTVNTHIEIRFHQLTVAISLGLYLIAYKSIEDINIMLFSLLVKPKPVVLATYYQKLAQVYWITNAHLLHAYALYKHYVYNKNYNMNFTQADSQLYSSVLLVAALSSPIQEVNQNQSLLQFDSQSQRAMGLASLLSLQSIPKRETFLVDVRKVTNEVYPELADLASIFEKKTSPLMFAKLLEPKIKFIEGHAQLSQYLKPFLRVVFTKIALQVSKVYEVIKIEEFIKLVPFYTKTQIELYLLESIKRKLIGARIDHKNGVIRFGHYDFDSAKISDQLSNLATGVGKALNMIEPEKKQQQHDKLKKEVYVKIINSLQDEHRRILARKEIIEKKKIYMEQQDRIKKQKEHEELQKKIQEKVARDQQRLKEDMERREKEQAEEESQQNQLDQTINAIDKAKVEMKAKIAKIAKQLYILERAYREEELPVVESLQKTKAVEDKQYFESTQAEFLKLHREVHDRNVTEKARLNRIVPEYQKFTQAVIEERKKQLPALQKEQEKRFQEFLIQQEQDVQERKAKREKARIAAAQEKARKEEQERERLEQEHLEQERLEEERKNAPYVPPSSRRTFRDDDDEREESGRWGGRRGGDDFGRSKADEGDRWGRREDAPPPRRDEGGDRWGRREDAPPPRRDEGGDRWGKREDAPPPRRDEGGWGRRDDAPPPRRDEGGDRWGRRDDAPPRRDDAPPPRRDDAPPPRRDEGGDRWGRRDDAPPRRDGGGSGGFGGRRDDAPPRRDEGGDRWGRREDAPPPRRDEGGDRWGRRDDAPPRRDGGGGSGFGRNQGAQGDQNDSWRSDNKKEENKKDADGWQTVGAKKRY

eIF3a

Eukaryotic translation initiation factor 3 subunit A

893 amino acids

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Belongs to the eIF-3 subunit A family.

106.035 kDa

MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYTYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSNNQTTGVSITKPETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMAMSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKEDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIRDVVRLNVPNLVSDEFRNLYNWLEVDFNPLNLCKRIQSIVDTIESTEKENTLLTPYIQSLKDVTIMRLIRQISQVYESIEFKRLLELAPFCNIFELEKLLVESVRHNDMQIRIDHQRNSIFFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSVVYPNRERDQRAKLRTQMVQHYHEIKDREHQRILQRQKIIEDRKEFIEKQNNARELEEARRHEDESRKAKQAEQKRLEQEQEKRERKRHENEIQAIKEKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAMRESEELQRERKELQSKIKSQEKKIDYFERAKRLEEIPLFEKYLAEKNVKDKEFWESTEQTRIELDIAERKDAVAQQARLQRMYPDRDEYLNALKKERASLYVEKLKKFEIALAEERKKRLADRIVRRREERRQAYLRAKEEERFRKEEEIRHAREAEERAAAEARRLEREAEDEKRRQQYEKQRAKEEEAERKIQEDRDRLAREVAVEPSTCFSRRRQ