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egg-2

Gene
egg-2
Protein
LDL receptor repeat-containing protein egg-2
Organism
Caenorhabditis elegans
Length
548 amino acids
Function
Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial (PubMed:16360684, PubMed:20971008). Redundantly with egg-1, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte (PubMed:16360684). Conversely, shown to be dispensable for fertilization but required together with egg-1 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane (PubMed:20971008). Appears to recruit or maintain together to the unfertilized oocyte cortex several proteins including chs-1, kinase mbk-2 and pseudophosphatase egg-3, and possibly egg-4 and egg-5 (PubMed:20971008).
Mass
59.288 kDa
Sequence
MSQQAGNAQRGRFDEEPMSLGEKISHRMDQLKEIVSSSCPCAGKFPPVAIVLIVALIILGVIIAVPLVIFLSPSAQAMSSGTRDLSSHSIRHPKVWPKTEKVQDDDLSAIQMTSLLPPNVSTCSGFGFACTGSIDMIIPSSKRCDGLKDCSDGSDEENCKECQSIYSCRAHIEEESEKKDKTSVLPTLICLTAEKLCNGVENCPDGSDEASCRSKCSKDQFKCSGSDACLPISVKCDGVSDCENESDESNCNKCQKGAHKCGKNCIKASKVCDGIPDCDDGSDEHQCDCKTCSGSEKALCEDGTCIMRSQVCDGKHDCLDGIDEENCPGSCSNERFSSKLKLLTCDDGNQYSEVEACSGLVEACELNCPKCDPKHTFTCPAVGGIHNKCIKRSKVCDGIFDCEDGADEKKCTPVKECVVESSIQFTCDNKCLESSRRCDGVWDCEDKSDEKGCDKCPSRSFKCSADKKCLPFHTRCNGVAECSDGSDEHKCSCQECLGTHHDTYMCSESNRCLKRGEVCSPYSMCPNATYIDKAYCASLALKNSGLRP

Gene
egg-2
Protein
LDL receptor repeat-containing protein egg-2
Organism
Caenorhabditis elegans
Length
548 amino acids
Function
Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial (PubMed:16360684, PubMed:20971008). Redundantly with egg-1, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte (PubMed:16360684). Conversely, shown to be dispensable for fertilization but required together with egg-1 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane (PubMed:20971008). Appears to recruit or maintain together to the unfertilized oocyte cortex several proteins including chs-1, kinase mbk-2 and pseudophosphatase egg-3, and possibly egg-4 and egg-5 (PubMed:20971008).
Mass
59.288 kDa
Sequence
MSQQAGNAQRGRFDEEPMSLGEKISHRMDQLKEIVSSSCPCAGKFPPVAIVLIVALIILGVIIAVPLVIFLSPSAQAMSSGTRDLSSHSIRHPKVWPKTEKVQDDDLSAIQMTSLLPPNVSTCSGFGFACTGSIDMIIPSSKRCDGLKDCSDGSDEENCKECQSIYSCRAHIEEESEKKDKTSVLPTLICLTAEKLCNGVENCPDGSDEASCRSKCSKDQFKCSGSDACLPISVKCDGVSDCENESDESNCNKCQKGAHKCGKNCIKASKVCDGIPDCDDGSDEHQCDCKTCSGSEKALCEDGTCIMRSQVCDGKHDCLDGIDEENCPGSCSNERFSSKLKLLTCDDGNQYSEVEACSGLVEACELNCPKCDPKHTFTCPAVGGIHNKCIKRSKVCDGIFDCEDGADEKKCTPVKECVVESSIQFTCDNKCLESSRRCDGVWDCEDKSDEKGCDKCPSRSFKCSADKKCLPFHTRCNGVAECSDGSDEHKCSCQECLGTHHDTYMCSESNRCLKRGEVCSPYSMCPNATYIDKAYCASLALKNSGLRP