dusp1-a

Dual specificity protein phosphatase 1-A

369 amino acids

Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-188' and 'Tyr-190', regulating its activity during the meiotic cell cycle.

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

40.264 kDa

MVNMETCAMDCCVLKALLAERAHKCLILDCRSFFSFSSCSIVGSSNVRLSTIVKRRAKGSMGLEHIVPNEEQRCRLVAGMYEAVVLLDERTSELDMLRKDSTMMLAVNALCRDSRGSSIYFLKGGYETFSAQCPEFCTKNSPPVGLSLPLCANNVPGSADSNCTPCGTPLYDQGGPVEILPFLYLGSAYHASRKDMLDTLGITALINVSANCPNHFEGHFQYKSIPVEDSHKADISSWFNEAIDFIDSVKNSGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPSCSAEAGSPTISVLDRGTSTTTVFNFPVSIPVHSGANSLSYLQNPITTSPSC