DUS1

tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]

423 amino acids

Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U16 and U17 in cytoplasmic tRNAs.

Belongs to the Dus family. Dus1 subfamily.

48.131 kDa

MTEPALSSANNALMQKLTGRQLFDKIGRPTRIVAPMVDQSELAWRILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLDGSSVDRPLVVQFCANDPEYLLAAAKLVEDKCDAVDLNLGCPQGIAKKGHYGSFLMEEWDLIHNLINTLHKNLKVPVTAKIRIFDDCEKSLNYAKMVLDAGAQFLTVHGRVREQKGQKTGLANWETIKYLRDNLPKETVFFANGNILYPEDISRCMEHIGADAVMSAEGNLYNPGVFNVGQTKNKEKIFPRVDKIIREYFQIVKECQESKASKTAMKSHFFKILRPFLPHHTDIRSTLATMNAKATWEEWEEQVVKPVEKVVQEIFEQPDIAIKDEITIGEKQSWGGSYRTVPYWRCQPYFRPVNGITGDKRVMQGLIDESVNKKRKADVPLESADKKKDVKA

dus1

tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]

399 amino acids

Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

Belongs to the Dus family. Dus1 subfamily.

45.327 kDa

MASKKLHGRDFYNKIGRPKRILAPMVDQSELPWRILARRSGADLCYSPMFHSRLFGESEDYRNKVFSTRTIPEERPLIIQFCGNDPEIMLKAAKIAAPYCDAVDVNLGCPQGIAKKGKYGSFLQENWNLIESIITKLHTELSIPVTAKIRIFPDPQKTLDYAKMILKAGASILAVHGRLREQKGHFTGIADWEQIQMLRKNLPSETVLFANGNILHAQDIDRCIKYTGVDGVLSAEGSLYNPRIFLPPSSPLMTLYPRIDDMCEEYLNIIREFKLESDYSSLSAIKGHLFKLMRPLLSIHTDIRSKLAQGCTPRDFETFPPVVAMLRKRLLECEEKGEINEDKDVKESVKDSMGYPVIPWWRVQPYIRPLEVPLVTKRKPVEVTADEGPVKKKVNASVA

dus1

Probable tRNA-dihydrouridine synthase 1

355 amino acids

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Belongs to the Dus family.

39.255 kDa

MGKCSYRFISLQTLTPNSLLDHSPNPTIWAKPLQIGSLTLHSRVLQSPLSGVTDLVFRRLVRRYAPQAMLYTEMVSATEIHHLRTLPQVMEIDPRENPISIQLFDCRPDFMAEAAQKAVAQGAQSVDINMGCPVNKITKKGGGSSLLRQPAVAEAIVKTVVAAVDVPVTVKTRLGWDDGEINIVEFAQRLQDAGAQMLTLHGRTRAQGYNGRARWQWIAKVKQALTIPVIANGDIFSVEAAIACLEETGADGVMCSRGSLGYPFLVGEIEHFFKTGEKRKAPTVAEKLTCAQEHLQMLWEYKGQRGLFQARKHLAWYCKDFPGAAALREQLFQINSVQEGKDLLDQAISTAKLCL

dus1

Probable tRNA-dihydrouridine synthase 1

333 amino acids

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Belongs to the Dus family.

37.066 kDa

MFKIGDIQLKNRVVLAPMAGVCNSAFRLTVKEFGAGLVCAEMVSDKAILYNNARTMGMLYIDEREKPLSLQIFGGKKETLVEAAKFVDQNTTADIIDINMGCPVPKITKCDAGAKWLLDPDKIYEMVSAVVDAVNKPVTVKMRMGWDEDHIFAVKNAQAVERAGGKAVALHGRTRVQMYEGTANWDIIKEVKQSVSIPVIGNGDVKTPQDAKRMLDETGVDGVMIGRAALGNPWMIYRTVQYLETGKLKEEPQVREKMAVCKLHLDRLIDLKGENVAVREMRKHAAWYLKGVKGNANVRNEINHCETREEFVQLLDAFTVEVEAKELQNAKVG