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doeB

Gene
doeB
Protein
N-alpha-acetyl-L-2,4-diaminobutyric acid deacetylase
Organism
Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)
Length
342 amino acids
Function
Involved in the biosynthesis of ectoine ((S)-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid) which is a highly soluble organic osmolyte, called compatible solute, use to avoid excessive water efflux, plasmolysis, molecular crowding of the cytoplasm, and cessation of growth in high salinity environments. Catalyzes the deacetylation of N-alpha-acetyl-L-2,4-diaminobutyrate (N-alpha-Ac-DABA) to yield L-2,4-diaminobutyrate (DABA).
Similarity
Belongs to the DoeB deacetylase family.
Mass
36.586 kDa
Sequence
MSKQPGQQRPSPISATVDFEADGVQHGFLKLPISNDESAWGAVMIPVTVVKRGEGPTALLTGGNHGDEYEGITALQKLSSRLRAEDVQGRVIIVPMMNTPACTAGRRTSPMDGGNLNRSFPGDPDGSVTEKIADYFTRVLVPMSDVVLDLHSGGRTLDIIPFAASHVLDDAEQQRRALEGAKAFGAPYAIMMFELDAEALFDTAVERQGKIFVATELGGGGTSTPESLAITERGIDNFLVHYGLVEGELQVPDEPQIYLDMPDASCYVQSEHTGLLELTVALGDPVTQGQVIARVYDMTRSGVAPVEYRAERDGVLAARRFPASVNMGDTIAVIAEVVESLG

Gene
doeB
Protein
N-alpha-acetyl-L-2,4-diaminobutyric acid deacetylase
Organism
Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)
Length
342 amino acids
Function
Involved in the biosynthesis of ectoine ((S)-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid) which is a highly soluble organic osmolyte, called compatible solute, use to avoid excessive water efflux, plasmolysis, molecular crowding of the cytoplasm, and cessation of growth in high salinity environments. Catalyzes the deacetylation of N-alpha-acetyl-L-2,4-diaminobutyrate (N-alpha-Ac-DABA) to yield L-2,4-diaminobutyrate (DABA).
Similarity
Belongs to the DoeB deacetylase family.
Mass
36.586 kDa
Sequence
MSKQPGQQRPSPISATVDFEADGVQHGFLKLPISNDESAWGAVMIPVTVVKRGEGPTALLTGGNHGDEYEGITALQKLSSRLRAEDVQGRVIIVPMMNTPACTAGRRTSPMDGGNLNRSFPGDPDGSVTEKIADYFTRVLVPMSDVVLDLHSGGRTLDIIPFAASHVLDDAEQQRRALEGAKAFGAPYAIMMFELDAEALFDTAVERQGKIFVATELGGGGTSTPESLAITERGIDNFLVHYGLVEGELQVPDEPQIYLDMPDASCYVQSEHTGLLELTVALGDPVTQGQVIARVYDMTRSGVAPVEYRAERDGVLAARRFPASVNMGDTIAVIAEVVESLG