Function
RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells. Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs (By similarity). Sequence-specific RNA-binding factor that binds to U-rich regions (URRs) in the 3'untranslated region (3'-UTR) of several mRNAs (By similarity). Does not bind to miRNAs (By similarity). Germline-specific protein required for the primordial germ cell (PGC) survival and migration during early embryonic development.
Sequence
MVGDMDAQQQELQQILNPQKLKSLQEWMQRNSITLTQVNGQRKYGGPPPGWQGPAPGSGCEVFISQIPNDVYEDRLIPLFQSIGTIYEFRLMMNFSGQTRGFAYAKYGDPLTASAAVTTLHQYRLPEGGCLTVRRSTEKRQLRLGDLPVSMNESKLLMVLQMLSDGVEDVLLKPPGPKGKEVVALVNYTSHYAASMAKKVLVEAFRNRYGISITVRWTSFSKSKRVEDTPQEDSCVTPLVLKPLSKPSLLHYDVPAHQSLLPLFRAVGGPTTSEQRDEMIPQPTIMSRNELIPQSSIRQRDEMVPQLPIRPRDGMAPQSPISLDAVSHLQWMCEVNRLGSPQYEVHFHHAAPDGFLYFAFKVLIPGLPLPLYGFVQILPGTSARAMKSEVYRAAAEQVIQTLCRVSNLRPF