dmt

Protein dalmatian

857 amino acids

Regulator of sister chromatid cohesion in mitosis. Probably involved in development of the central nervous system.

96.513 kDa

MVRTRPVPCVPSPDVNTATRRNPGRPKKQSIGADLSTTISKPGRPKKLSIGADLTTIRKPGRPKKLGADLTTIIRKPGRPTKLSNKQSLTALNEPECRIRKCVVKIRRIKVKNGVVSEISRNDAPDVDASTFEPARNSTMYIPSKVQKSTQPQNIKENVAGPETSPCQQRIRSKSPSGPAAEISPKKPPRFFHRDQPLTRTRSSVTRNVFDFLSQSQIEDDSDREDPAADIIQRLVKDGKACVMVRSRKIGKPRAKRTAKKVRPVGNRRKVSTKDNEPEPVKVVPKSIEPRLQKPSRSLSTIFEPEEDYSNDSEHGYVQPIEVPVQVHVEPSTSKQAHEGAYSNLARSVMLNQTQAQNPLPSTDRRRELINMARQLVSTPLNRRAPPVTDVSATTTALSPIAHQSPNAVRTAGGKSPWRVSDDSPLPNTFMFGFNNSQMPSYSSDHVQRRHVYVPDSPVEHAENIPHEESICPPLHEQNHDSNANDSNEENRPPPTISKSMSINDQESEENAENFVHLPNPRRTLQKRTPFKDINILEVVTLPSWKKNVTATVSKEITPTRVAPRPMATSSPAQRSQTRSNLFGFDDDFACEDIPRKSTTPSKGIAPTSMSLNREVTPALANRNQTEVNTFGCNEILPCENIPKEKETNTEERTSSSQNLFGFDEFITESQDSPANFTGLSQNVNLHDKLHRLAELRPRDGELPQVSYTSIRSDCLGESHSKQTDIRYMLCSTMIAPPRPAKRKPAAPTARESMGLFRVDQDEPEQSFADKQPRRTYVKERPQRKRKKRVQILYIESESEDEDEQDSHDKSLDSPEKKRHHVKRPRRDIEHEAKLEQFVTSFNKQCEEVEKFPVIIE

dmt

Methyltransferase Dmt

754 amino acids

Methyltransferase that methylates adenine residues in the dsDNA sequence GATC. Essential for genome packaging because it methylates GATC sequences within the pac site making the latter cleavable (PubMed:3312202, PubMed:2236019). May prevent degradation of viral DNA by the host restriction-modification antiviral defense system (PubMed:376871).

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

83.628 kDa

MKELCYGSVCSGIEAASIAWEPLGMRPAWFAEIEPFPSAVLAHRWPHVANLGDMTKLAKKVLAGEIESPDVLVWGTPCQAFSIAGLRGGLDDERGALTLKYVELANAIDDKRSESFLKPTVIVWENVPGVLSSADNAFGCFLAGLAGEDAPFEPGDRPESGKSNAFWRWDGKTGCHAPKWPQCGCIYGPQRKVAWRILDAQYFGVAQRRRRVFVVASARTDLDPATVLFEFEGVRRNIAPRRKKKEIASAIIANGAAISGESLNPCLHADMPPSMKSTKAVNAFRMAAFGEYIDDETASTVKARDFKDATDLAVFSSTGAGFWSEGHGTLRAREQESHEHLVTLAFPERMSGTQHAATKNTSPSLMAKNPTAVCYEVRNAEVAVRRLTPVECERLQGFPDGHTLIPTEKRKKVNSDELAYLRNHYPDLSEEEAAMLAADGPRYKAIGNSMAIPVMRWIGDRITKAVCRQKEGSETKERKVKPAAEFERSIFKWAGGKFGVLEQIFRYLPEGKRLIEPFVGGGAVFTNAGYQENLLNDVNADLINFYKTLQREAHSLITLAHRFFQDYNTQEGYLAVRNAFNKQVYDDLHRAAAFLFLNRHCFNGLTRYNQAGEFNVGYGKYKTPYFPLQEMEAFLGAEGRSEFVCGDFAAVIEAAGEGDVIFCDPPYEPLPNTEGFTNYSGHDFKFEEQKRLVSLLTDAHRRGAKVLITNSGAPNIRELYHDSGFRVEPLFARRSVSCKGDTRGVAHDVLGILL

dmt

Methyltransferase Dmt

754 amino acids

Methyltransferase that methylates adenine residues in the dsDNA sequence GATC. Essential for genome packaging because it methylates GATC sequences within the pac site making the latter cleavable (PubMed:3312202, PubMed:2236019). May prevent degradation of viral DNA by the host restriction-modification antiviral defense system (PubMed:376871).

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

83.628 kDa

MKELCYGSVCSGIEAASIAWEPLGMRPAWFAEIEPFPSAVLAHRWPHVANLGDMTKLAKKVLAGEIESPDVLVWGTPCQAFSIAGLRGGLDDERGALTLKYVELANAIDDKRSESFLKPTVIVWENVPGVLSSADNAFGCFLAGLAGEDAPFEPGDRPESGKSNAFWRWDGKTGCHAPKWPQCGCIYGPQRKVAWRILDAQYFGVAQRRRRVFVVASARTDLDPATVLFEFEGVRRNIAPRRKKKEIASAIIANGAAISGESLNPCLHADMPPSMKSTKAVNAFRMAAFGEYIDDETASTVKARDFKDATDLAVFSSTGAGFWSEGHGTLRAREQESHEHLVTLAFPERMSGTQHAATKNTSPSLMAKNPTAVCYEVRNAEVAVRRLTPVECERLQGFPDGHTLIPTEKRKKVNSDELAYLRNHYPDLSEEEAAMLAADGPRYKAIGNSMAIPVMRWIGDRITKAVCRQKEGSETKERKVKPAAEFERSIFKWAGGKFGVLEQIFRYLPEGKRLIEPFVGGGAVFTNAGYQENLLNDVNADLINFYKTLQREAHSLITLAHRFFQDYNTQEGYLAVRNAFNKQVYDDLHRAAAFLFLNRHCFNGLTRYNQAGEFNVGYGKYKTPYFPLQEMEAFLGAEGRSEFVCGDFAAVIEAAGEGDVIFCDPPYEPLPNTEGFTNYSGHDFKFEEQKRLVSLLTDAHRRGAKVLITNSGAPNIRELYHDSGFRVEPLFARRSVSCKGDTRGVAHDVLGILL