Protein
Doublesex- and mab-3-related transcription factor DM-W
Function
Transcription factor that plays a key role in female sex determination and primary ovary development. Acts as a sex-determining protein by antagonizing the transcriptional activity of male-determination protein dmrt1-a, acting as a dominant-negative type protein.
Similarity
Belongs to the DMRT family.
Sequence
MQNNEEPYNTGQYPSGPHGKKSPRLHKCARCRNHGYATPLKGHKRFCIWRDCQCQKCSLITERQRVIAAQVALQRQQAQEEELGIYHPIPLPIAAVIKREHGGSSSQLMLESSSTQTTSTPTSAEWIKEEEVAKPAAGLFAPPPSSEEMGMTLAAVGAADAATQTDQPGHLFNMMSAMIQQLMDMSWELQQGWI