dkgB

Gene

dkgB

Protein

2,5-diketo-D-gluconic acid reductase B

Organism

Corynebacterium sp. (strain SHS752001)

Length

277 amino acids

Function

Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 25DKGR-B has higher catalytic efficiency than 25DKGR-A.

Similarity

Belongs to the aldo/keto reductase family.

Mass

30.548 kDa

Sequence

MPNIPTISLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGRAVRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWPNPSVGRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAFHDEHGIRTESWSPLARRSELLTEQLLQELAVVYGVTPTQVVLRWHVQLGSTPIPKSADPDRQRENADVFGFALTADQVDAISGLERGRLWDGDPDTHEEM

Protein

2,5-diketo-D-gluconic acid reductase B: dkgB

Gene

dkgB

Protein

2,5-diketo-D-gluconic acid reductase B

Organism

Escherichia coli O157:H7

Length

267 amino acids

Function

Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).

Similarity

Belongs to the aldo/keto reductase family.

Mass

29.439 kDa

Sequence

MAIPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAAVGLAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKEGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRENLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD

Protein

2,5-diketo-D-gluconic acid reductase B: dkgB

Gene

dkgB

Protein

2,5-diketo-D-gluconic acid reductase B

Organism

Escherichia coli (strain K12)

Length

267 amino acids

Function

Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).

Similarity

Belongs to the aldo/keto reductase family.

Mass

29.437 kDa

Sequence

MAIPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAAVGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRKNLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD

Protein

2,5-diketo-D-gluconic acid reductase B: dkgB

Gene

dkgB

Protein

2,5-diketo-D-gluconic acid reductase B

Organism

Salmonella typhi

Length

267 amino acids

Function

Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).

Similarity

Belongs to the aldo/keto reductase family.

Mass

29.26 kDa

Sequence

MTIPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESGVPRNELYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADHIATNQIELSPYLQNRKVVDWAKAHGIHITSYMTLAYGKALKDEVIARIAVKHNATPVQVILAWAMGEGYSVIPSSTRRENLASNLLAQDLHLDAEDKNAIAALDCNDRLVSPEGLAPAWD

Protein

2,5-diketo-D-gluconic acid reductase B: dkgB

Gene

dkgB

Protein

2,5-diketo-D-gluconic acid reductase B

Organism

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

Length

267 amino acids

Function

Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).

Similarity

Belongs to the aldo/keto reductase family.

Mass

29.153 kDa

Sequence

MTIPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESGVPRNELYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADNIATNQIELSPYLQNRKVVDWAKAHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTRRENLASSLLAQDLHLDAEDKNAIAALDCNDRLVSPEGLAPAWD

Protein

2,5-diketo-D-gluconic acid reductase B: dkgB

Gene

dkgB

Protein

2,5-diketo-D-gluconic acid reductase B

Organism

Yersinia pestis

Length

267 amino acids

Function

Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).

Similarity

Belongs to the aldo/keto reductase family.

Mass

29.035 kDa

Sequence

MSIPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAIQESGINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWPSPNDEVSVAEFMSELLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVVDFAKQNGIAVTSYMTLAYGKALAEPVIKTIAEQHGATPAQVILSWAMQLGYGVIPSSTKAANLASNLLAQKLCLNAADMALIATLDRNERLVSPDGLAPKWD

Protein

2,5-diketo-D-gluconic acid reductase B: dkgB