dhlC

2-haloacid dehalogenase, configuration-inverting

296 amino acids

Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (R)- and (S)-hydroxyalkanoic acids, respectively, with inversion of configuration at C-2. Acts on 2-haloalkanoic acids whose carbon chain lengths are five or less.

Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

32.785 kDa

MTNPAYFPQLSQLDVSGEMESTYEDIRLTLRVPWVAFGCRVLATFPGYLPLAWRRSAEALITRYAEQAADELRERSLLNIGPLPNLKERLYAAGFDDGEIEKVRRVLYAFNYGNPKYLLLITALSESMQMRPVGGAEVSSELRASIPKGHPKGMDPLLPLVDATKASTEVQGLLKRVADLHYHHGPASDFQALANWPKVLQIVTDEVLAPVARTEQYDAKSRELVTRARELVRGLPGSAGVQRSELMSMLTPNELAGLTGVLFMYQRFIADITISIIHITECLDGAEAASKSPFPI