Protein
Hybrid signal transduction histidine kinase E
Organism
Dictyostelium discoideum
Function
May act in a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
Sequence
MDKLKINNNLSPPSSPSSSTTTPNLSSTNLENNLNSNINNNINNFNLNNSTNTFNNSNNIIINNNNNNNNNNNNNNNNNNNNSNNNNNNINNNNPNVNSPNEVILNNNFLKQNKKGFFKRNKKMIEIFLPPKFKSPIYRRCCILLGECGVYVFIYMFFLIFLRSFYPIFICGIVSMIVLYIVSTKTTKYKLVALIYIFVQSILNFTFFLQITNNFNNNTVNINNTDDYSNEVIEFSKLNFLFIMNLILSLISIQIFFPKFTFSITLTCSLNIFNIIIHLISIYSLNTKKLIVFQNLIVPITVSFLLSFYSYILSIDNQEIEAKEKRFRNIFDTSSEALVIHKNGLIIDVNSTFEKIFQIKQSDLINGTIWEYLPELESFFQNTNGNSKYTNQSLQQQLQQQQQQQQQLYNTITNGGNNKQTSTTSANSTPRYNNYNNNNINSNNLNNLNVFNNLNNLNNLNNNNNNHHIHKVSRSNTGLSDSSSIFDDSDSVDFFSMKNINKCPIVLDTVGITPCGSEFCAQVKIERKKDMLIGSGTSSFNLLNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNSNNNNNNNNINNNISNNIINNNNNNNNSGIITNLSQQSNNLSTTNLNTSSKIINHKHKNSKQDFDVMSIVDISAKKKLMIADQALRRAEELNQAKINFLTTVSHEVRTPINGILASVEILDGSQLDVTQRDFLSCIKQSADYLLDLITDILDFSKIEAGKFELDRVEFNLITMLEESINIVYRTAQERGIEVLTFIDPDVPIILIGDPYRVKQCVLNFLSNAIKFTHKGQVMVKVSIVDQINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKIVGFSNNNNNNNNNNNNGNNGILNFKLSFSVEDSGVGIKEEVLDCLFTPFHQLGGSPRKYLGTGLGLSISKKLTTLMGGEIGVKSVYGVGSAFSFTSILSTTSTTPISLQSLGSSLSIALNNLSPTIPKISGFIYDDNIHTSNSLFNFLKLMNINLKIINPIINNNNNNNNNNNNNNNNNNNNNNNNNNNNNDNNNNNNNNNDNNIDQQQLKFEFENEIDKYCNVEDDNNNVILIITNQLSNDNLNYFKDKINQLNNSIYWFVLCDNGLKAIDPFYYGIVKKPNNLLNLVDTVFKVYNCQLPQDLYQLLTNGSKDDYKNYLKYRNVVIKKITEDNEKKQQQQQQQQQQMGDTLSSTKSPQYTNLPPLDISSSSNGSLNKSNRSNLLRKSSSVYSDHVAITRGMVQVNRSPRPSTPPPLFNLKGNNSNPNSTELNSTNSVNGNPNNDSTLETIEPLNISETVGDLCSSGSVINNSNFIINNNFLTSSPYGSCLTPNSGTTSPSIPININNNDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSFKKLEPDNFSPPPSILINDNNIIPALNVTTPITISTSTSSSSSLLINNEINNKSTTSKRPSFIPPLDIQSKKLIINTADENHKNNCIIDFEQIFGQDGKQQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQKLNIGNQQQQQILSSPRLQSQLLSNCDSLGNTPPVTPHRRNALIVDDTELNRKVLAQLLRRMDWSVSFAENGIEALKEITSERCFDIIFMDCQMPILDGFETTKLLRLRELENNWKPLNIVALSADSSSSFGQVCFDCGMNGYLGKPITLITLKDTLLKWGGYRD