dhak

Probable dihydroxyacetone kinase

648 amino acids

Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

Belongs to the dihydroxyacetone kinase (DAK) family.

71.006 kDa

MKKIINNPQNVVSEMIDGFTQSSRDLLKLKGNFNVVVRSDYSQIKDRVTLISGGGSGHEPAHIGYIGNAMLTGAVCGDVFASPSAKQIFMAIKSVAGKMGCILIVKNYMGDNGSFSIAREMCKSQLPDIRVEIITVDDDISSILMKLNEFSNDNNDNIQDIRDKYKSITNRRGIAGTVLVHKILGGLAEQGKSIDEILKFYNKYISPSKSLNLVTMGVGLSSCIIPSVGSPSFTLNEKEMEIGLGIHGEFGIEKVELKPSKQIIKSLIDNLLKILPYSNNNNNNNNNNNNNNNNNNNNNNNSCGISCGSDGEDKSLIVLINNLGSTTNMEMAIATNDCLNYLHEKGFTVERLITGTLMTSLEMAGISISLLLIKNNQIINLIDLKTNAMGWPNSVLKPYKNKEDSILTLDENDSHEIKYDNLKSITISKENGEILKEIVLLGCNSLIENSNKLTDLDKQVGDGDLGTTLENLSKSIKKSIDTIPFDKPCYTFRKISLIIQELIGGSSGLFYSIFFLRLSNSLYERSTVNGKNQISTNDWGLSLIDAVNAIKELGKADIGDCTMLDSLIPAINKINQCCKDNENSSSSFDLLNTLKLASKEAQLGSESTIEMIAKKGRSSYLGERTSHIMDPGAHAIEIIFKSFLSIKK

dhaK

Dihydroxyacetone kinase

552 amino acids

Catalyzes the phosphorylation of dihydroxyacetone.

57.94 kDa

MSQFFFNQRTHLVSDVIDGAIIASPWNNLARLESDPAIRIVVRRDLNKNNVAVISGGGSGHEPAHVGFIGKGMLTAAVCGDVFASPSVDAVLTAIQAVTGEAGCLLIVKNYTGDRLNFGLAAEKARRLGYNVEMLIVGDDISLPDNKHPRGIAGTILVHKIAGYFAERGYNLATVLREAQYAASNTFSLGVALSSCHLPQETDAAPRHHPGHAELGMGIHGEPGASVIDTQNSAQVVNLMVDKLLAALPETGRLAVMINNLGGVSVAEMAIITRELASSPLHSRIDWLIGPASLVTALDMKGFSLTAIVLEESIEKALLTEVETSNWPTPVPPREITCVVSSHASARVEFQPSANALVAGIVELVTATLSDLETHLNALDAKVGDGDTGSTFAAAAREIASLLHRQQLPLNNLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGANVVEALNTGLAQMKFYGGADEGDRTMIDALQPALTSLLAQPKNLQAAFDAAQAGAERTCLSSKANAGRASYLSSESLLGNMDPGAQRLAMVFKALAESELG

dhaK

PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK

356 amino acids

Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP (PubMed:15476397, PubMed:11350937). Binds covalently dihydroxyacetone in hemiaminal linkage (PubMed:15476397). DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR (PubMed:24440518). In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity (PubMed:24440518). In the absence of dihydroxyacetone, DhaL-ADP is converted by the PTS to DhaL-ATP, which does not bind to DhaR (PubMed:24440518).

38.215 kDa

MKKLINDVQDVLDEQLAGLAKAHPSLTLHQDPVYVTRADAPVAGKVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTSPTPDKIFECAMQVDGGEGVLLIIKNYTGDILNFETATELLHDSGVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLVGAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIHGEPGIDRRPFSSLDQTVDEMFDTLLVNGSYHRTLRFWDYQQGSWQEEQQTKQPLQSGDRVIALVNNLGATPLSELYGVYNRLTTRCQQAGLTIERNLIGAYCTSLDMTGFSITLLKVDDETLALWDAPVHTPALNWGK