Protein
Dihydrofolate reductase
Organism
Staphylococcus haemolyticus
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Sequence
MWSFLKISLIVAMDKKRVIGKDNDIPWRISSDWEYVKNTTKGHAIILGRKNLQSIGRALPDRRNIILTRDKNFNFKDCEIAHSIEAAFKLCENEEEVFIFGGEQIYVMFLPYVEKMYVTKIHHEFEGDTFFPVVNFDDWKEVSVEKGIKDEKNPYDYYFHIYERIR