der1

Gene

der1

Protein

GTPase Der

Organism

Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)

Length

481 amino acids

Function

GTPase that plays an essential role in the late steps of ribosome biogenesis.

Similarity

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.

Mass

53.903 kDa

Sequence

MLPVVALVGRPNVGKSTLFNRLTNTRDALVADYPGLTRDRKYGQAKFEKRQFIVVDTGGITGDEEGIDAEMAQQSLLAIEEADVVLFLVDARAGLLPADQGIADHLRRINKQIFVVANKVDGIDGDSESAEFYSLGLGAIKQIAAAHGRGVSQLLQDALKPLESDFPDMEIIDEAPEEEEDAESQRQRLQELPIKLAIVGKPNVGKSTLTNRILGEERVVVYDMPGTTRDSVYIPMERDEREYILIDTAGVRKRKKISEAVEKFSIVKTLQAIEEANVVLLVIDAREGITDQDLSLLGFVLNSGRSLVVAVNKWDGLSTDIKDDIKREMDRRLGFIDFARIHFISALHGSGVGNLFESVQEAYMSATKRINTALLTQIMEMAQDDHQPPLVRGRRVKMKYAHAGGYNPPVIVIHGNQVDDLPSSYKRFLMNYFRKALEIMGTPIKIEFREGNNPFEGKKNNLTLAQQRKRRRMMSYYKEKK

Protein

GTPase Der: der1

Gene

DER1

Protein

Derlin-1

Organism

Oryza sativa subsp. japonica

Length

242 amino acids

Function

May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins.

Similarity

Belongs to the derlin family.

Mass

27.532 kDa

Sequence

MSSPAEYYNSLPPISKAYGTLCFFATVLCQLQILNPPFLALYYPFVFKKFQIWRLFTSFFFLGKFSINFGIRLLMIARYGVQLEKGAFEKRTADFLWMMIFGAISLLALSAIPFLDIYFLGVPMVSMLLYVWSREYPNSQISMYGLVQLRSFYLPWAMLGLDVIFGSEILPGLLGILVGHTYYFLSVLHPLATGKNYLKTPMWVHKIVARFRIGVQANAPVRPAAANTGSGAFRGRSYRLSQ

Protein

Derlin-1: DER1