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denB

Gene
denB
Protein
Endonuclease IV
Organism
Enterobacteria phage T4
Length
185 amino acids
Function
Cleaves single-stranded DNA in a dC-specific manner. The cleavage occurs exclusively at the 5'-proximal position (dC1) within a dCs tract having a minimal size of 6 bases. These specific cleavages may have a detrimental effect on the replication of host dC-containing DNA.
Mass
21.161 kDa
Sequence
MQKTNPGLQRLFQIPTFTLSNSDLTCEMKVKIADTARYSLKQNPNQDKAEVIERCRIAVYAEFFVADWLSGYVNKGQEDVDDPYTYAWDVLAHPKYCGLRVEVKTHQTDSRWISVTTGCSGEYPYGSGINLGPILNHQVADCIIIFNTKEIHPGVIQYTPKFIGDREDLRKVVRKSNYNGWYLSI