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def4

Gene
def4
Protein
Peptide deformylase 4
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Length
216 amino acids
Function
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
Similarity
Belongs to the polypeptide deformylase family.
Mass
24.184 kDa
Sequence
MAQQDTDQQHPGVLPVDDEGFVVDSQDCEEREADWRGRGTSRPITVVGNPVLHKECEDVTDFGEEFQQLVADMFASQRTAEGVGLAANQIGVSKKVFVYDCPDDEGVRHVGVVCNPRLVELPADRRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPVKVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND