Protein
Modification methylase DdeI
Organism
Desulfomicrobium norvegicum (strain DSM 1741 / NCIMB 8310)
Function
This methylase recognizes the double-stranded sequence CTNAG, causes specific methylation on C-1 on both strands, and protects the DNA from cleavage by the DdeI endonuclease.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Sequence
MNIIDLFAGCGGFSHGFKMAGYNSILAIEKDLWASQTYSFNNPNVSVITEDITTLDPGDLKISVSDVDGIIGGPPCQGFSLSGNRDQKDPRNSLFVDFVRFVKFFSPKFFVMENVLGILSMKTKSRQYVKDIIAEEFSNVGYKVCVIILNACDYGVPQSRQRVFFIGLKSDRPLNQQILTPPSKVIESEYTSLEEAISDLPVIEAGEGGEVQDYPVAPRNKYQENMRKGSTCVYNHVAMRHTQRLVDRFAAIKFGQSVKHVSEEHSQRKRGDANSISGKVFSQNNMRPYPYKPCPTVAASFQSNFIHPFYNRNFTAREGARIQSFPDTYIFQGKRTTMSWEKHLSQYQQIGNAVPPLLAQALAERISWYFENINLINDSNVSIKRMVQRSFMSQLNLENNVNVRQDDNYDKVHSF