Protein
Dynactin subunit 2-A
Function
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity).
Similarity
Belongs to the dynactin subunit 2 family.
Sequence
MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFKDKKVGTRSLDFSDRITKSKRTGYESGEYEILGEGIGMKETPQQKYQRLLHEVQELTQEVEKTQSTVKESAAEEKLTPVALAKQVASLKQQLVSTHLEKLLGPDAAINLTDPDGALAKRLLTQLDAAKTRKNPEGKSPAKGPGPDTENLVTYELHCRPEQNKFSQAAKMAELEKRLGELEVAVRCDQDTQNPLTVGLQGSCLMDTVEILQAKVNLLDVASLDQVEARLQSVLGKMNEIAKHKAAIEDADTESKVHQLYETVQKWDSMSGTLPQVVQRLLTLKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTNALAMVQKAMKENLATVEDNFSNIDGRIKKLSK