Protein
Conserved virulence factor B
Organism
Staphylococcus aureus (strain NCTC 8325)
Function
Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection.
Similarity
Belongs to the CvfB family.
Sequence
MALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDDDELEVGEEYSFFIYPNRSGELFATQNMPDITKDKYDFAKVLKTDRDGARIDVGLPREVLVPWEDLPKVKSLWPQPGDYLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNEVIEAKPYRVLRIGSFLLSESGYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSFLPLAHERLDDDGQVIFDLLVEYDGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQKIINIETGKIALTKKGWSRMDSKE