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ctsR

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Length
155 amino acids
Function
Binds to the ftsH promoter region, leading to repression of its expression.
Similarity
Belongs to the CtsR family.
Mass
17.614 kDa
Sequence
MQSQNISDIIEKYLKSILADSEHVEIRRSEIADLFNVVPSQINYVIKTRFTIQNGYLVESKRGGGGYIRIEKVNLVDDADVLDALIQVIGDSITQRDAYAVVQSLYEDDVLNRREAQLILVAIDHETLGLTDRDLENSLRARIIIGILNHLRYES

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Bacillus subtilis (strain 168)
Length
154 amino acids
Function
Controls the expression of the cellular protein quality control genes clpC, clpE and clpP, as well as mcsA and mcsB. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock, CtsR is degraded by the ClpCP and ClpEP proteolytic systems, ensuring the derepression of clpE, clpP and the clpC operon. CtsR negatively autoregulates its own synthesis.
Similarity
Belongs to the CtsR family.
Mass
17.744 kDa
Sequence
MGHNISDIIEQYLKRVLDQNGKEILEIKRSEIADKFQCVPSQINYVINTRFTSERGYIVESKRGGGGYIRIIKIKMNNEVVLINNIISQINTHLSQAASDDIILRLLEDKVISEREAKMMVSVMDRSVLHIDLPERDELRARMMKAMLTSLKLK

Gene
ctsr
Protein
Transcriptional regulator CtsR
Organism
Geobacillus stearothermophilus
Length
153 amino acids
Function
Controls the expression of the cellular protein quality control genes clpC, clpE and clpP, as well as mcsA and mcsB, by acting as a repressor of these class III stress genes. After heat shock, CtsR is degraded by the ClpCP and ClpEP proteolytic systems, ensuring the derepression of clpE, clpP and the clpC operon. CtsR negatively autoregulates its own synthesis (By similarity).
Similarity
Belongs to the CtsR family.
Mass
17.872 kDa
Sequence
MPNISDIIEQYLKQVLNMSDQDIVEIKRSEIANKFRCVPSQINYVINTRFTLERGYIVESKRGGGGYIRIMKVKTKSEAQLIDQLLELIDHRISQSSAEDVIKRLMEEKVISEREAKMMLSVMDRSVLYIDLPERDELRARMLKAMLTSLKYK

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus aureus (strain USA300)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.842 kDa
Sequence
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus aureus (strain NCTC 8325)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.842 kDa
Sequence
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus aureus (strain bovine RF122 / ET3-1)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.851 kDa
Sequence
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIHAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus aureus (strain COL)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.842 kDa
Sequence
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.842 kDa
Sequence
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus aureus (strain N315)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.842 kDa
Sequence
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus aureus (strain MRSA252)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.842 kDa
Sequence
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus aureus (strain MSSA476)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.842 kDa
Sequence
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus aureus (strain MW2)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.842 kDa
Sequence
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.784 kDa
Sequence
MHNMSDIIEQYIKRLFEEADEDVVEIQRAHIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQGYYVIDGLLDKGLINEREAKMIQTIIDRETLKMDVVARDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus epidermidis (strain ATCC 12228)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.784 kDa
Sequence
MHNMSDIIEQYIKRLFEEADEDVVEIQRAHIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQGYYVIDGLLDKGLINEREAKMIQTIIDRETLKMDVVARDIIRANILKRLLPVINYY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus haemolyticus (strain JCSC1435)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
17.759 kDa
Sequence
MHNMSDIIEQYIKKLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQIIGPSISQQQAYYILDGLLDKGLISEREARMIQVIVDRETLKMDVVARDIIRANILKRLLPIINFY

Gene
ctsR
Protein
Transcriptional regulator CtsR
Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)
Length
153 amino acids
Function
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Similarity
Belongs to the CtsR family.
Mass
18.02 kDa
Sequence
MHNMSDIIEQYIKKLFEDTNEDVVEIRRTNIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDETGYINHLLQLVGPSISQQQAYYIVDGLLDKSYINEREAKMIYAVIDRETLKMDILSRDIIRANIIKRLLHVINYY