Function
This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen.
Similarity
Belongs to the CTP synthase family.
Sequence
MKYILVTGGVISGIGKGVIASSVGTILKSSNLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQSVINKERKGDYLGKTVQVVPHITEAIQEWVMRQALIPVDEDGIEPEVCVIELGGTVGDIESMPFVEAFRQFQFKARRENFCNIHVSLVPQPSATGEQKTKPTQNSVRELRGLGLSPDLVVCRCSTPLDTSVKEKISMFCHVEPQQVICVHDVSSIYRVPLLLEEQGVVDYFRQRLDLPIGRQPRRLLMKWKEMADRYERLLESCSIALVGKYTKFSDSYASVIKALEHSALAINHRLEIKYIDSADLEQETLQEEPVRYHEAWQKLCSSDGILVPGGFGVRGTEGKIQAIAWARKQKKPFLGVCLGMQLAVVEFARDVLDWKDANSTEFNPKTSHPVVIDMPEHNPGQMGGTMRLGKRRTIFHSQNSVMKKLYGGHEYVEERHRHRYEVNPELRRELEARGLKFVGQDTEGERMEIVELEDHPYFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSQYIERGCRLSPRDTYSDRSENSSPDAEIAELKLPMIDHE