Protein
Serine/threonine-protein kinase cst-1
Organism
Caenorhabditis elegans
Function
Serine/threonine-protein kinase which extends lifespan and delays tissue aging, probably by activating daf-16.
Similarity
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Sequence
MPPSTDSSRRNSEEGSSDGFKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFIKNAPGCDIMQLMIQDAQEKAILGQAPMAASSGNDATLLSEGMSTMIDGGESTLVQHKDNYVTAQSLRSQMESLRIGGEIPKSAYIPGSSKNGNSPRVQPPGHTASASDPSKNQPFAQDGTGPNFQLGTSESSYKDASYNMMNTEAEYENRFQRAVVDGDFEFLRNITLDELIRRKESLDSEMEEEIRELQRRYKTKRQPILDVIEIKKRLQ