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cpox

Gene
CPOX
Protein
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Organism
Homo sapiens
Length
454 amino acids
Function
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
Similarity
Belongs to the aerobic coproporphyrinogen-III oxidase family.
Mass
50.152 kDa
Sequence
MALQLGRLSSGPCWLVARGGCGGPRAWSQCGGGGLRAWSQRSAAGRVCRPPGPAGTEQSRGLGHGSTSRGGPWVGTGLAAALAGLVGLATAAFGHVQRAEMLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRRPGDMKTKMELLILETQAQVCQALAQVDGGANFSVDRWERKEGGGGISCVLQDGCVFEKAGVSISVVHGNLSEEAAKQMRSRGKVLKTKDGKLPFCAMGVSSVIHPKNPHAPTIHFNYRYFEVEEADGNKQWWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDLYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEVFRFVQSCARAVVPSYIPLVKKHCDDSFTPQEKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPSENSKEAEILEVLRHPRDWVR

Gene
Cpox
Protein
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Organism
Rattus norvegicus
Length
443 amino acids
Function
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (By similarity).
Similarity
Belongs to the aerobic coproporphyrinogen-III oxidase family.
Mass
49.278 kDa
Sequence
MALRLGQLGSGPWWRAVRGDYAQLRAPSPRSASACVCRLPGTAGTQPRRGLGHGSSAGGGSRLGTGLAAALAGMAGLAAAVLGHVQRAEMVPKSSGARSPSPGRLEEDGDELARRCSTFMSSPVTELRELGRRPDDMKTKMELMIMETQAQVCRALAQVDGVADFSVDRWERKEGGGGITCVLQDGRVFEKAGVNISVVHGNLSEEAANQMRSRGKALKKKDGKLPFTAMGISSVIHPKNPYAPTMHFNYRYFEVEEADGKMHWWFGGGCDLTPTYLNREDAVHFHRTLKEACDQHGPDIYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEAFRFVKTCAEAVVPSYVPIVKKHCDDSYTPQDKLWQQLRRGRYVEFNLVYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPPENSKEAEILEVLRHPKDWVH

Gene
cpox
Protein
Oxygen-dependent coproporphyrinogen-III oxidase
Organism
Dictyostelium discoideum
Length
332 amino acids
Function
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (By similarity).
Similarity
Belongs to the aerobic coproporphyrinogen-III oxidase family.
Mass
38.266 kDa
Sequence
MTSTNEPIPTEEEIKNGFKFIQDEICKFLITTTGGHQQYSEDKWDYTKGSGGGISRVWEGKEEEGFYLNQDYQSQNNKCDKIEKGGVNFSYIVGSNLPSAAATQFKIAPDTKYIATGVSLVIHPYNPNVPTIHMNVRYFEAGDVWWFGGGVDLTPVYPKLDQVVEFHSTLKKVCDQYGQEENKTSYALGKAECDSYFFLPHRGETRGVGGLFFDHLKSDKAKTWKFIYQLGLSFIDLYKPFLVNNSSISYDKVQREYQLYRRSRYVEFNLLFDRGTKFGILSEGRTESILMSLPAVCKWKYNYKPEENTPEANLLTFLRPRDWLNENQENKN