Protein
4-hydroxybenzoate polyprenyltransferase, mitochondrial
Organism
Caenorhabditis elegans
Function
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
Similarity
Belongs to the UbiA prenyltransferase family.
Sequence
MITRSIGIARRSNSINCIVGSNTSTSYSLDESTKRWISTSTKQPMSLIPTASSLVASSPPNLKPYLQLMRVDKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLACGSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGLTFNWGALLGWCALKGDLSSSAPFWMYAAALQWTLIYDTIYAHQDKADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQTWPYYVALAATTAQLGWQVGTVDIDNGSDCWDKFKSNSWMGIILFSGIVASTLLKEVFQILIRPYH