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cope-1

Gene
cope-1
Protein
Coatomer subunit epsilon
Organism
Caenorhabditis elegans
Length
292 amino acids
Function
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
Similarity
Belongs to the COPE family.
Mass
32.803 kDa
Sequence
MADKLFSIRNYFFLGSYQSCIGEALKFSSKNEEEKQEKDVYLYRSYIAQGQAFIPLKEIPAATKSADLAAVRRYAEFRNNPAAKKKILAEVQEEVASRNIKSEIAAVLAATILNEADLSQDAFRAVSRFEGLEARASKVFILIKMNKRKLAIGEVKKMNQIDEDATLSQLANALVTSFGASGKVKDALYIYSEMSDKYGRTTDLEMHQAVVSILTQDYAAAEELLESALERDNKDADVLINSIVSAQLNEKDDDVVERFISQLKHEHPNHPWVIDFNEKEAEFDRVASDSRA