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comX

Gene
comX
Protein
Competence pheromone
Organism
Bacillus subtilis
Length
58 amino acids
Function
Part of a major quorum-sensing system that regulates the development of genetic competence. Acts through the activation of the two-component regulatory system ComP/ComA composed of a sensor histidine kinase, ComP, and a response regulator, ComA, that regulates directly the transcription of over 20 genes. Transport through the membrane may involve Spo0K. Under certain conditions plays a role in sporulation.
Mass
6.684 kDa
Sequence
MKQDMIDYLMKNPQVLTKLENGEASLIGIPDKLIPSIVDIFNKKMTLSKKCKGIFWEQ

Gene
comX
Protein
Competence pheromone
Organism
Bacillus subtilis subsp. spizizenii
Length
58 amino acids
Function
Part of a major quorum-sensing system that regulates the development of genetic competence. Acts through the activation of the two-component regulatory system ComP/ComA composed of a sensor histidine kinase, ComP, and a response regulator, ComA, that regulates directly the transcription of over 20 genes. Transport through the membrane may involve Spo0K. Under certain conditions plays a role in sporulation.
Mass
6.684 kDa
Sequence
MKQDMIDYLMKNPQVLTKLENGEASLIGIPDKLIPSIVDIFNKKMTLSKKCKGIFWEQ

Gene
comX
Protein
Competence pheromone
Organism
Bacillus subtilis (strain 168)
Length
55 amino acids
Function
Part of a major quorum-sensing system that regulates the development of genetic competence. Acts through the activation of the two-component regulatory system ComP/ComA composed of a sensor histidine kinase, ComP, and a response regulator, ComA, that regulates directly the transcription of over 20 genes. Transport through the membrane may involve Spo0K. Under certain conditions plays a role in sporulation.
Mass
6.518 kDa
Sequence
MQDLINYFLNYPEALKKLKNKEACLIGFDVQETETIIKAYNDYYLADPITRQWGD