Protein
Chloronitrobenzene nitroreductase
Organism
Comamonas testosteroni
Function
Involved in the biodegradation of chlorinated nitroaromatic compounds. Catalyzes the reduction of 4-chloronitrobenzene to yield 1-hydroxylamino-4-chlorobenzene. Probably also able to catalyze the two-electron reduction of nitrobenzene (NB) to produce a nitrosobenzene (NOB) intermediate, which is immediately reduced to hydroxylaminobenzene (HAB) by a second two-electron transfer.
Similarity
Belongs to the nitroreductase family.
Sequence
MPTSPFIDDLIRDRRTKRGFLDQPVPIEMVKDILSVAKYTPSSSNTQPWRCYVLTGEARERVTTAAVEAYRGAPEGLKPEYSYFPEPLHEPYATRFNSFRGQLGDAEGCCRSDITGRRRYVERQFRFFDAPVGLIFTMDRRLEWASFICYGCFLQNIMLAAKGRGLDTCPQGLWSLQHPVLRTELNLPDDQMVVAGMSLGWADNSMAVNQMSMSRVELEEFTTFVHE