Protein
CDGSH iron-sulfur domain-containing protein 2A
Organism
Oncorhynchus mykiss
Function
Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy (By similarity).
Similarity
Belongs to the CISD protein family. CISD2 subfamily.
Sequence
MVLETISRIIKIQLPAYLKKLPLPETIGGFARLTVSDWLRLLPLLGILALLGYLTIRPFLPKKKKQKDSLINLEIQKENPKVVNEIDIEDLNRTNVCYCRCWRSKTFPVCDKSHIKHNELTGDNVGPLILKKKIL