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chol-2

Gene
chol-2
Protein
Phosphatidyl-N-methylethanolamine N-methyltransferase
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
214 amino acids
Function
Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
Similarity
Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
Mass
23.587 kDa
Sequence
MPLVALGVADLFNFVDYSKTSLAISAAAIAFNPTFWNIVARREYRTKFLTRAFGGNAQVACYFLAVTIFGLGLVRDFLYERALRDQPSHPLLEGTYVKYAAYALLALGNLLVITSTMRLGITGTFLGDYFGILMDGIVTGFPFNVTSAPMYYGSTMSFLGTALLYGKPAGLLLTAWVLFVYIIAIQFENPFTAEIYAKRDRERAKAAGTSKKEL