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chl-1

Gene
chl-1
Protein
ATP-dependent DNA helicase chl-1
Organism
Caenorhabditis elegans
Length
830 amino acids
Function
Required for normal cell proliferation and chromosome stability. Plays a role in DNA repair during replication.
Similarity
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
Mass
94.65 kDa
Sequence
MDEFSFPFQPYDIQLNLMREIRQCIEQRKIGIFESPTGTGKSLSVLCSTMTWLEAEELRISTDLSTRLGEVHTKITECDKITTADNWETAVREKMRAQDVETEILEQIQSRERLQSRIDQARRGMVEVSRKRKAPARDTDQFLEPQDEAAPSEEYNNDEKSEKQRDSDFFDDVDEEEEKPLKCLKIFYASRTHSQLEQLAEELAKTRFQPRIVTCASRGTLCVNEEVKKLKLNHLINEKCMELRKNGMSEKEKVQKLEKGTTKKTKTCATSCEFYNSTQIEDVVNGVLSNKLKSTLEVSKQGKLSNGCPYFATRKSVPQCQLVLLPYQVLLHDGTRKAWGIELKDNVIVLDEAHNVLNTISSLYSAEISTKSLTLALRLIREYNAHYKLKLLAHNLLYMKQLESLTSKMLIFLNSQSKEDVMTMAQLARNLNILEINLFKLAEYMEKTDLCKKFHGFYMRLQKEEIKKENEKPKLTGIQKLMAAKEAEPEPEAEPLPPPKPVPSPLFSLKSFIDALTNKCEDGRIIVEKSATEAKFRFMLLNPADRLSEVVTSARATILVGGTMEPAQLLVETLSRGSIGADSIRRFSCCHVIDDSQLLAVTVERTVDGKPFQLTYQTRGADTTLRSLATSIQALIPHIPNGVVIFVPSYDFLFNFQKKMKEFGILKRIEEKKAVFTESRQPTSDVWDRFSRAAKTSKGAILFAVVGGKMSEGINFCDELGRAVIVIGLPYPNKTSVELRERMKFLDTQMPNGGNLLYESLCMHAVNQAIGRAIRHRRDYAAVYLFDDRYAKESTRRKLSTWIGDRTQVKLGFGEIIRKTRSFFEANSKK