Protein
Modification methylase CeqI
Organism
Rhodococcus hoagii
Function
This methylase recognizes the double-stranded sequence GATATC, causes specific methylation on A-? on both strands, and protects the DNA from cleavage by the CeqI endonuclease.
Sequence
MVVTSSAGCASRPRGRGRWPRLSRRSGCLEVPGRPRRPFLRPTVPGPTSARPRRGRAPHGRSTRCTGWRVQLSFSCPPFIKNRQFQFYLIRSPFSRVGYGLSDVNSSSLLGLWGIKFFACWENSNMIYIFKMLGYNQDKLPITSERLVPMASSISPEKLGAKIVEWYSCIVSREVEQAEEYKQEIGQLVNQLERSDEKVLSYYSLVLFRHQLLTEDVQQKRVEPTSLQAVNVEDTIYDGLLAFLYYFMSGQYEFYEGRYQSALRLYKIAEQKIDHVHDQSEKAEFYFRLGESYFAHHQYTFAVSYLEQAIDLFENNNFIWTILNCRLLLAAIKTELNLFDEAEKEYQSALADATPYPTTHALLLRALGLNRVRQRKLYEAEMYFAEALTIGDHSKSVEGLKTKANLANVRLRQNANNAEAIRLLQEAKAGATAIHLEECMVRCAITEALYINEGRDERLTSELQRLLEREFYTEYSELAEEIAEYYKQQSLLEKAFYYMKEALHYRTNMKMIGVEQQ