cdk5rap1

Gene

cdk5rap1

Protein

CDK5RAP1-like protein

Organism

Dictyostelium discoideum

Length

607 amino acids

Function

Probable regulator of CDK5 activity.

Similarity

Belongs to the methylthiotransferase family. MiaB subfamily.

Mass

69.876 kDa

Sequence

MINRLNRLCKKNILNNILNNNKNVSNRIINRFYCNLNTTNLKINNDNNLKESIREKIKDIPSLNEFLRNSNNEINENNENKSKIETEEEYELPPYLSSLPNDKGNGRKVWIETYGCQMNVSDEEVICSIMKSSGYTISNDFNTADIVFLNTCSIRENAEAKIWLRLTELRAIRRKQGRPNLIVGVLGCMAERLKEKLLESDMKVDIVVGPDAYRSLPSLLATLEDGEQQTAINVILSADETYADIKPVRKSDNQVSAYVSIMRGCNNMCSYCIVPFTRGRERSRPIDSILREVKDLSDQGFKEITLLGQNVNSFNYYEESNNNNNENFIDTQKNKLELESLKPREGFKTIYKSPKKGITFTKLMELVSKVDPEIRIRFTSPHPKDFPDDLLELIKNQPNICKQLHIPAQSGSSKVLESMRRGYTRESYIELIDTIKRVLPGCAISSDFISGFCGESDQDHNETISLMEYVGYENAFMFMYSLREKTHAHRQLKDDVPTTLKNSRLTQVVDTFYKRLKEKNQLEIGNHHLVLVDGFSKRSEKDFVGRTDTNKKVLISNDIENQDIKVGEYYIVEIIKGDSEVTLKGKPIMKSSIQHFNNIYNHKNKFI

Protein

CDK5RAP1-like protein: cdk5rap1

Gene

CDK5RAP1

Protein

CDK5 regulatory subunit-associated protein 1

Organism

Homo sapiens

Length

601 amino acids

Function

Specifically inhibits CDK5 activation by CDK5R1.

Similarity

Belongs to the methylthiotransferase family. MiaB subfamily.

Mass

67.689 kDa

Sequence

MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLAAGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQVFLPPRPPKVLGLQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC

Protein

CDK5 regulatory subunit-associated protein 1: CDK5RAP1

Gene

Cdk5rap1

Protein

CDK5 regulatory subunit-associated protein 1

Organism

Mus musculus

Length

588 amino acids

Function

Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity).

Similarity

Belongs to the methylthiotransferase family. MiaB subfamily.

Mass

66.11 kDa

Sequence

MHPLRCVLQVQRLSAPFTSMCWVLLRTCRAQSSVSSTPCPSPEAKSSEAQKDFSSRLATGPTFQHFLRSASVPQEKPSSPEVEDPPPYLSGDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKVLKTKRPRSRVPLRIGILGCMAERLKGEILNREKMVDLLAGPDAYRDLPRLLAVVESGQQAANVLLSLDETYADIMPVQTSPSATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPVASILDEVRKLSEQGLKEVTLLGQNVNSFRDNSEVQFNNAGSANLSRGFTTNYKPKQGGLRFSHLLDQVSRIDPEMRIRFTSPHPKDFPDEVLQLIRERHNICKQIHLPAQSGSSRVLDAMRRGYSREAYVALVHHVRETIPGVSLSSDFITGFCGETEDDHRQTVSLLREVQYNTGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITVFREEASKANKTSVGCSQLVLVEGFSKRSTTDLCGRNDANLKVIFPDAEVEDITNPGLKVRAQPGDYVLVKITSASSQTLKGHILCRTTMKDSLTYCTT

Protein

CDK5 regulatory subunit-associated protein 1: Cdk5rap1

Gene

Cdk5rap1

Protein

CDK5 regulatory subunit-associated protein 1

Organism

Rattus norvegicus

Length

586 amino acids

Function

Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1.

Similarity

Belongs to the methylthiotransferase family. MiaB subfamily.

Mass

65.866 kDa

Sequence

MHPLQRVFRAQRLSAPLTSMCWVLLRTFRAHNSTSCPDPEGKSSEGVQKDFSSRLATGPTFQHFLRSASVPQEKPSSPEVEDPPPYLSGDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKVLKAKRPRSRVPLRIGILGCMAERLKGEILNREKMVDLLAGPDAYRDLPRLLAVVESGQQAANVLLSLDETYADIMPVQTSPSATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPVASILDEVRKLSEQGLKEVTLLGQNVNSFRDNSEVQFSSTGSANLSRGFTTNYKPKQGGLRFSHLLDQVSRIDPEMRIRFTSPHPKDFPDEVLQLIRERHNICKQIHLPAQSGSSRVLEAMRRGYSREAYVALVHHIREAIPGVGLSSDFITGFCGETEDDHLQTVSLLREVQYNTGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITVFREEASKVNATSVGCTQLVLVEGFSKRSTTDLCGRNDANLKVIFPDAEVEDITDPGLKVRAQPGDYVLVKIISASSQTLKGHILCRTTMKDSSMNCLT

Protein

CDK5 regulatory subunit-associated protein 1: Cdk5rap1