Protein
Probable cell cycle serine/threonine-protein kinase CDC5 homolog
Organism
Encephalitozoon cuniculi (strain GB-M1)
Function
Protein kinase required for the cell cycle where it is involved in mitotic exit. Required to form a bipolar spindle, the actin ring and septum. Functions upstream of the whole septum formation pathway, including actin ring formation (regulated by late septation genes) and septal material deposition (regulated by early septation genes). Behaves as a 'septum-promoting factor', and could also be involved in inducing other late events of cell division (By similarity).
Similarity
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
Sequence
MSTKVELYMEIGTVITDLEYHTKYMLKKLLGRGAYAQCYLAEIESGEQYAMKVVRLKDIKSRKVHEKLESEIAIHSKLDNPNVVKMYRSFRSSEYVFMVLELCERGALDALLKRNGKLKERHVARFVKQTVEGLIYLHNSVSVVHRDLKLGNLFLDSKFNVKIGDFGLSAVIKDGEKKVTMCGTPNYIAPEVLFGKASGHSFEADIWSLGVIIYTLLVGVPPFQKKNVEDIYKMIKLNNYIFPENCDLSSEAIDLITQILNTNPLERPTLEHILSHKFLSKKEHFLMKIYRNLMTNRTEEGVVDTDYVLFSIPVTKLRGVGYVLKSGVYGIYFSDHRNLMLKPNRKSVIYLNSTIESGKRVFYKEEHLVEKIPAEIAESYKGLQYFIRTFDNGFSFLDVEPCFIVKIRKIECGFLFVMADSTIVFDFVDGWRVVLSRCGERVSCYNGLGLASFNQEIRGRCIEILRGCLGCG