Protein
Probable MFS transporter cctQ
Organism
Talaromyces islandicus
Function
Probable MFS transporter; part of the gene cluster that mediates the biosynthesis of the mycotoxin cyclochlorotine, a hepatotoxic and carcinogenic cyclic chlorinated pentapeptide (PubMed:26954535). With the ABC transporter cctS, is most likely responsible for cyclochlorotine secretion and thereby may contribute to intrinsic resistance (PubMed:26954535).
Similarity
Belongs to the major facilitator superfamily.
Sequence
MGQKETFYRNWNGGGDFLRTVFGLGGLDHTNDSPAEQRYVNSLETSSMMAENDIGSLMPLVYTTVAFFVAVVLPHGSPMSNSHSSKKAFALLNWPRVLTSRNIWSISHGIFAASMFGSFWVQSAVGTIPLFGIVGFSWAVTCRIPYYLLHDELYRSSTQRNRQGDDLTDSQGLIHGIHNFSICLAQIVVLLMINTVWILASDDDGDSFLVWFLLLGGACALLAMYFTTRLREPENIKYEEIAMEEGDYGFSE