About Products Protein Database Contact

ccno-b

Gene
ccno-b
Protein
Cyclin-O protein B
Organism
Xenopus laevis
Length
365 amino acids
Function
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of mcidas to promote mother centriole amplification and maturation in preparation for apical docking.
Similarity
Belongs to the cyclin family.
Mass
40.662 kDa
Sequence
MVTCSMRCTEEGLLGATLAFSSGKRKRDSVYSPGDATPGDRGEGEPKCPSVGTKKRAKYSRHRKQSLELRSCDSGVADLYETPSPSPVAPSPTHEPWDTCTPMYDGLGLQNFRDYGQDCYTFNKSLEDKFLAVNCLKNQPQIQAESRCKLISWLIPVHRHLNLGFESLCLTVNILDRFLACTPVASDCFQLVGVTSLLIASKQVETRPPRVKQLLALCCDAFSREQLCNLECIILLKLHFRLGAPTINFFLQHFSLLRVTNEESSDTELSETTKSVTVARGIAELSLADYAFNSYSPSLMAVCCLEIADRMLCHRNPIRARVSDYHESLIQECVGKIDLLVSLNQDSLHRLLPSQFAVKSINVDN