Protein
Thiol:disulfide interchange protein DsbE homolog
Organism
Paracoccus denitrificans (strain Pd 1222)
Function
Required for disulfide bond formation in some periplasmic proteins. Also acts as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur.
Similarity
Belongs to the thioredoxin family. DsbE subfamily.
Sequence
MARFSPMMLLPVAIFAGFAGLSGWALLRDDPDALPSAMIGREAPSVGEATLPGKVQLTDEMLRQPGVKLVNFWASWCPPCRAEHPTLTELSARLPVYGVDLKDPEGAALGFLSEHGDPFHALAADPRGRVAIDWGVTAPPETFIIDGSGRILHRHAGPLVREDYTNRFLPELEKALAAE